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Cardiac Output, Low clinical trials

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NCT ID: NCT06418022 Recruiting - Shock Clinical Trials

Evaluating Fluid Responsiveness in ICU Patients Using VTI and Trendelenburg Positioning

TREND-US
Start date: April 1, 2024
Phase: N/A
Study type: Interventional

Fluid administration is a commonly performed in the ICU for critically ill patients. However, it can lead to complications such as fluid overload, pulmonary edema, and increased mortality in some patients. Therefore, identifying patients who are likely to respond to fluid therapy is crucial for optimizing their management. Several methods have been used to assess fluid responsiveness, such as passive leg raising, stroke volume variation, and cardiac output monitoring. However, these methods have limitations and may not be feasible in all patients. In this study, the investigators aim to evaluate the use of velocity time integral (VTI) and Trendelenburg positioning in predicting fluid responsiveness in ICU patients.

NCT ID: NCT06355882 Recruiting - Clinical trials for Low Cardiac Output Syndrome

Patients With Low Cardiac Output Syndrome Undergoing Local Dental Anesthesia

Start date: August 8, 2023
Phase: N/A
Study type: Interventional

Patients with low cardiac output syndrome requiring surgical and periodontal dental treatment will be selected to undergo the dental procedure using local dental anesthetic: 2% lidocaine with epinephrine and 2% lidocaine without vasoconstrictor. Cardiovascular events and the safety of using two cartridges (3.6 mL) will be evaluated. They will be evaluated by Holter monitoring in the period of 1 hour before, during and 1 hour after the procedure and blood pressure correction will be performed

NCT ID: NCT06088966 Recruiting - Cardiac Output, Low Clinical Trials

Evaluation of Hemodynamic and Ventilatory Effects of Negative Pressure Ventilation

Start date: August 1, 2023
Phase:
Study type: Observational

Investigation of the effects of negative pressure ventilation after cardiac surgery in adults onto performance of the left and right heart and the lungs.

NCT ID: NCT05905536 Recruiting - Cardiac Output, Low Clinical Trials

Perioperative Monitoring of Cardiac Surgery Patients With the Vitalstream Physiological Monitor

Start date: August 15, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to validate cardiac output and stroke volume derived from Vitalstream against Gold Standard measurements obtained using thermodilution. The Vitalstream device is a continuous noninvasive physiological monitor (Caretaker Medical LLC, Charlottesville, Virginia, further referred to as "CTM") provides heart rate, continuous noninvasive blood pressure (BP), respiratory rate, stroke volume and cardiac output.

NCT ID: NCT05492968 Recruiting - Cardiac Output, Low Clinical Trials

The Effect of Epinephrine, Norepinephrine and Phenylephrine on Intraoperative Hemodynamic Performance

RACE
Start date: September 1, 2022
Phase: Phase 4
Study type: Interventional

The use of catecholamines for blood pressure and hemodynamic management is essential during undergoing surgery. The type of the catecholamine with the most clinical meaningful effect is still unknown. Therefore, the investigators evaluate the effect of intraoperative continuous infusion of epinephrine, norepinephrine and phenylephrine on intraoperative cardiac output. The investigators further evaluate the effect of epinephrine, norepinephrine and phenylephrine on regional brain and regional tissue oxygenation during surgery.

NCT ID: NCT05035719 Recruiting - Cardiac Output, Low Clinical Trials

Comparison Studies Comparing Hemodynamic Parameters Provided by the Caretaker Against Respective Gold Standard References

Start date: March 1, 2021
Phase:
Study type: Observational

Comparison studies comparing hemodynamic parameters provided by the Caretaker against respective Gold Standard references.

NCT ID: NCT04885699 Recruiting - Cardiac Output, Low Clinical Trials

Validation of Capnodynamic Assessment of Mixed Venous Oxygen Saturation

Start date: June 1, 2021
Phase:
Study type: Observational

Mixed venous saturation (SvO2) is an indicator of the balance between oxygen supply and demand in the body's tissues Recently, our research team published a paper describing the possibility to continuously monitor SvO2 by the use of continuous dynamic capnography (Karlsson et al, A Continuous Noninvasive Method to Assess Mixed Venous Oxygen Saturation: A Proof-of-Concept Study in Pigs. Anesth Analg 2020) The primary objective of the current study is thus to investigate the agreement and trending ability for capnodynamically derived SvO2 against the gold standard CO-oximetry. The secondary objective is to investigate the agreement and trending ability for capnodynamically derived CO (COEPBF) against the modified CO2-Fick method.

NCT ID: NCT04871620 Recruiting - Surgery Clinical Trials

Reliability of a New Pulse Contour Technique for Diagnosing an Increase in Stroke Volume During a Fluid Challenge for Hemodynamic Optimization in Patients Scheduled for High-risk Abdominal Surgery: Comparison With Transthoracic Echocardiography: COMPARE Study

COMPARE
Start date: January 1, 2016
Phase:
Study type: Observational

The present study aims at assessing the ability of a new pulse contour device for diagnosing a >15% stroke volume (SV) increase during patient hemodynamic optimization by fluid challenge in high risk abdominal surgery.

NCT ID: NCT04755764 Recruiting - Pregnancy Related Clinical Trials

Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy

Start date: March 3, 2021
Phase:
Study type: Observational

The purpose of the research is to characterize the effect of labetalol, atenolol, and nifedipine on maternal hemodynamics early in pregnancy. Patients will be given medication based on their hemodynamics and asked to return for a repeat measurement.

NCT ID: NCT04698005 Recruiting - Clinical trials for Hemodynamic Instability

Exogenous Ketones for Acutely Decompensated HEart Failure

KADHEF
Start date: December 2, 2020
Phase: Phase 3
Study type: Interventional

This study will evaluate whether supplementation of exogenous ketones in patients with severe left ventricular dysfunction and acutely decompensated heart failure requiring inotropic therapy would improve the patient's hemodynamics and symptoms.