Effectiveness of a Cancer Exercise Program

Cancer Clinical Trial

Official title:

The Impact of an 8-week Exercise Program on Physical Function in Individuals With Cancer

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT06039488
• Other study ID #: Pro00109975
• Status: Enrolling by invitation
• Phase: N/A
• Start date: August 15, 2021
• Est. completion date: January 2027

Study information

• Verified date: September 2023
• Source: University of South Carolina
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The investigators are examining the impact of an 8-week multi-modal exercise program (resistance and cardiovascular training) delivered 2 times per week on physical function adults (>18 years old) with cancer.

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 150
• Est. completion date: January 2027
• Est. primary completion date: January 2026
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adults > 18 diagnosed with cancer

Exclusion Criteria:

• unwilling to come to the on-site clinic for exercise sessions

• any neuromuscular, cardiovascular, or psychological condition precluding safe exercise

• unable to read/understand English.

Related Conditions & MeSH terms

• Cancer

Intervention

Behavioral:
• Exercise
A combination of resistance exercise and cardiovascular exercise (performed 2 days per week for 8-weeks) is tailored to each individual in accordance with their medical/cancer-related history, baseline assessments of physical function, and overall goals. Resistance exercise includes 6-8 exercises targeting major muscle groups. The first week of the program is used to familiarize participants to the exercises of the program, provide coaching on safe and appropriate technique, and identifying initial load for 2 sets of 12 repetitions (equivalent to ~65% 1 repetition maximum), with a goal of working towards 4 sets of 8 reps. Additionally, participants are asked to perform 20-30 minutes of moderate-to-vigorous aerobic activity (approximately 60-85% age-predicted heart rate maximum) via walking, jogging, or cycling each session.

Locations

Country	Name	City	State
United States	University of South Carolina	Columbia	South Carolina

Sponsors (1)

Lead Sponsor	Collaborator
University of South Carolina

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Bellarmine Norton Assessment Tool (2-minute Step Test)	2-minute Step Test: Number of times an individuals' knee reaches a predetermined heigh during a 2-minute period of marching	0 and 8-weeks
Primary	Bellarmine Norton Assessment Tool (Timed Arm Curl)	Timed Arm Curl: Number of repetitions an arm curl individuals can complete in 30 seconds)	0 and 8-weeks
Primary	Bellarmine Norton Assessment Tool (30 second Chair Stand)	Chair Stand: Number of times participants can stand from a sitting position and return to sitting in 30 seconds	0 and 8-weeks
Secondary	Fatigue	The Functional Assessment of Chronic Illness Therapy (FACIT) Fatigue Scale: The FACIT-Fatigue scale is a 13-item scale that will be used to assess cancer-related fatigue. The FACIT-Fatigue scale is scored on a 0-4 response scale from 0 = "not at all" to 4 "very much", regarding items related to fatigue and energy in the past 7 days. Lower score indicates greater fatigue	0 and 8-weeks