Cancer Clinical Trial
Official title:
Evaluation of the Improvement of Autonomic Nervous System by a Physical Rehabilitation Program Adapted to Adulthood After Chemotherapy or Radiotherapy in Childhood
Survival rate of childhood cancers is now reaching 80%. However, early or late complications
related to surgery, chemotherapy and radiotherapy remain high and greatly increase the risk
of late mortality.
Health of individuals is closely correlated to the stability of the autonomic nervous system
(ANS), a key system for maintaining homeostasis in any living species. Efficient computer
tools allowed the opportunity to assess the intrinsic autonomic regulation of the ANS either
directly or at a later time by an analysis of the heart rate variability (HRV). These tools
have become very powerful predictors of cardiovascular morbidity and neurological aging.
Physical endurance training improves both maximal aerobic capacity and ANS activity.
The main objective of this study is to evaluate improvement of ANS parameters after 6 months of adapted physical activity in adults treated for childhood cancer in Rhône-alpes region in France who have deregulation ANS or autonomic imbalance. ;
Observational Model: Cohort, Time Perspective: Prospective
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