Cancer Clinical Trial - I125 Brachytherapy After TURP

Status Completed

Clinical Trial Summary

Low dose rate brachytherapy using iodine 125 is well established as a treatment for low and intermediate risk prostate cancer. Currently there is uncertainty as to the safety of this technique in patients who have had a previous transurethral resection of the prostate gland (TURP) for obstruction of the urine flow through the prostatic urethra. Early experience when the technique was being developed in the 1980s suggested that there was a higher incidence of urinary incontinence after brachytherapy if there had been a previous TURP. It is however clear that with increasing experience many centres offer this treatment to patients who have had previous TURP, using various parameters to select patients including time from the TURP and persence or absence of a significant cavity within the gland on MRI scanning. There has been no systematic study of I125 brachytherapy after TURP in the current era which might address and inform the practice for future patient. Hence this study is designed to formally assess the safety of I125 brachytherapy after previous TURP.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Cancer

Clinical Trial Details

NCT number	NCT02370992
Study type	Observational
Source	The Leeds Teaching Hospitals NHS Trust
Contact
Status	Completed
Phase
Start date	July 1, 2011
Completion date	July 1, 2016

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