3D Single Cell Analysis Using Cell Morphology and Organelle Scattering Texture

Cancer Clinical Trial

Official title:

3D Single Cell Analysis Using Cell Morphology and Organelle Scattering Texture

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02335463
• Other study ID #: 201402039RINB
• Status: Recruiting
• Phase: N/A
• First received: January 7, 2015
• Last updated: October 13, 2016
• Start date: May 2014
• Est. completion date: April 2017

Study information

• Verified date: October 2016
• Source: National Taiwan University Hospital
• Contact: JENGWEI TJIU
• Phone: 886-2-23123456
• Email: jengweitjiu[@]gmail.com
• Is FDA regulated: No
• Health authority: Taiwan: Department of Health
• Study type: Observational

Clinical Trial Summary

The investigators will use an advanced high resolution 3D optical coherence tomography (OCT) technology to observe colon and skin images in ex vivo.

Description:

Achieved formalin-fixed paraffin embedded tissue specimens from colon cancers and/or other benign and pre-cancer colon lesions as well as melanoma and/or other benign pigmented skin lesions will be used. The achieved specimens were kept in Department of Pathology, National Taiwan University Hospital. Sections of achieved pathological specimens were put on glass slides and tissue image will be observed by 3D optical coherence tomography (OCT). The 3D optic tomography system utilize a Ce:YAG optical fiber as light source and also combined with confocal microscopy. Taken together, these features made the 3D optic tomography system have very high resolution and suitable for single cell imaging. This study will not interfere with the normal medical practice and had no impact on patient's safety and health. All of the materials will be destroyed once the experiments are done. The enrollment criteria will be patients who underwent colon/skin surgery or examinations in NTUH with pathological specimens taken and stored at NTUH.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. completion date: April 2017
• Est. primary completion date: April 2017
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 20 Years and older

Eligibility

Inclusion Criteria:

• Participants are those who who received skin or colon surgery, with their surgical specimens preserved and stored at Department of Pathology, National Taiwan University Hospital.

Exclusion Criteria:

• Age younger than 20 years old.

Study Design

N/A

Related Conditions & MeSH terms

• Cancer

Locations

Country	Name	City	State
Taiwan	National Taiwan University Hospital	Taipei City

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Image of colon or skin tissue	Image of colon or skin tissue	1 day	No