Cancer Clinical Trial
Official title:
Diffusion-weighted MRI at 3T Using an Endovaginal Coil: Evaluating the Prognostic Value of the Apparent Diffusion Coefficient Distribution in Stage 1 Cervical Tumours
This study aims to develop the technique of Diffusion-Weighted Magnetic Resonance
Imaging(DW-MRI)for the assessment of stage 1 cervical cancers. An endovaginal receiver coil
has been designed and developed at the Institute of Cancer Research and Royal Marsden NHS
Foundation Trust for use at high field strengths(3T). This will be used to evaluate if DW-MRI
at 3T can be used to differentiate different histological characteristics within whole
tumours and so determine if the technique could be of prognostic value.
The study hypothesis is that this technique will be able to differentiate tumours with
histological features known to be associated with poor prognosis (tumour type, grade and
lymphovascular space invasion).
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