Cancer Clinical Trial
Official title:
Prospective Analysis of the Nutritional Status of Chemo-radiotherapy Patients
Cancer patients are one of the patient groups at highest risk for the development of
malnutrition. Anti-cancer treatments, such as chemotherapy and radiotherapy, can further
heighten the risk due to the nutrition-related toxicities experienced during this time.
This study aims to baseline the nutritional status of chemo-radiotherapy patients undergoing
treatment at the Alan Walker Cancer Care Centre (Darwin), identify contributors to
nutritional deterioration and determine if there is a difference between Indigenous and
non-Indigenous patients.
Background: Cancer patients are at a greater risk of malnutrition. Limited data exists on the
development of malnutrition during chemo - radiotherapy, particularly in rural and remote
areas of Australia. Additionally, there is no data on the nutritional status of cancer
patients in the Northern Territory or areas with a high proportion of Indigenous Australians.
While considering the aforementioned dearth of literature, we are conducting a study in
Darwin, Northern Territory of Australia. This study aims to establish a baseline of the
nutritional status of chemo - radiotherapy patients undergoing treatment at the Alan Walker
Cancer Care Centre (Darwin), to identify contributing factors to nutritional deterioration,
and to determine if there is a difference between Indigenous and non-Indigenous patients.
This study will provide a prospective analysis of malnutrition and a clear insight of
nutritional status of cancer patients. It presents the first of its kind to address the
nutritional status of cancer patients in Indigenous Australians.
Methods/ design: Using the Patient Generated-Subjective Global Assessment; all eligible
patients will be assessed for malnutrition and consented for participation into this study.
Each participant's nutritional status will be assessed at baseline, first week of treatment,
final week of treatment, and at one month post treatment. Prevalence data will be analysed
using percentages. Comparative data will be analysed using chi-square tests. A linear
regression analysis of the results will be undertaken. Data will be analysed using SPSS
version 20 (IBM SPSS).
Discussion: Weight loss and malnutrition among cancer patient is well documented, however,
results from our study might appear to be more remarkable when compared with the other
published data, because of our participants demographic, assessment tool used: the Patient
Generated-Subjective Global Assessment has not been validated for use in Indigenous
Australian Keywords: Nutritional status, malnutrition, prospective analysis,
chemo-radiotherapy
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