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NCT01084785 Clinical Trial

Biobank Carcinoma: Storing Blood and Protein of Patients With Cancer

Cancer Clinical Trial

— Biobank  

Official title:
Storing Blood for Analysis of DNA and Protein of Patients With Cancer in MAASTRO Clinic

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT01084785
Other study ID # 08-06-23/01
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date January 2003
Est. completion date January 2026

Study information
Verified date April 2022
Source Maastricht Radiation Oncology
Contact Philippe Lambin, Prof PHD
Phone 31 (0) 088 44 55 666
Email philippe.lambin@maastro.nl
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study is to determine, by means of DNA and protein analysis, the relationship between DNA and protein profiles and a number of endpoints, which are important for the patient such as overall survival and side effects.

Description:

It has already been known for a long time that cancer is a genetic disorder and that the development of the illness is a very complex interaction between genetic and surrounding factors. Also the response on therapy and the development and seriousness of side effects is stipulated by this complicated collaboration of genetic and surrounding factors. Moreover it is not only the DNA that plays an important role but also the systems of control at protein level. At this moment a lot of questions remain to be answered because up till now the studies were of rather restricted statistic strength with frequently inconsistent dates and moreover retrospective. Major retrospective studies are necessary to distinguish the relationship between DNA/protein patterns and clinical relevant endpoints like prognosis and toxicity in which an as broad as possible patient group is being monitored. For this reason we want to take blood samples in MAASTRO clinic of all patients with lung cancer and to store it encrypted so that we can perform DNA and protein analyses in future and to correlate the results with survival and toxicity of the treatment.

Other known NCT identifiers
  • NCT00157352
  • NCT00157365
  • NCT00157391
  • NCT00157404
  • NCT00157417
  • NCT00157430
  • NCT00157443
  • NCT00157456
  • NCT00157469
  • NCT00157495
  • NCT00181337
  • NCT00181376
  • NCT00181389
  • NCT00181402
  • NCT00181415
  • NCT00181428
  • NCT00181441
  • NCT00181454
  • NCT00181467
  • NCT00181480
  • NCT00181493
  • NCT00181519
  • NCT01067872

Recruitment information / eligibility
Status Recruiting
Enrollment 10000
Est. completion date January 2026
Est. primary completion date January 2026
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - cancer Exclusion Criteria: - not able to comply with follow-up

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Netherlands Maastricht Radiation Oncology Maastricht Limburg

Sponsors (2)
Lead Sponsor Collaborator
Maastricht Radiation Oncology Maastricht University Medical Center

Country where clinical trial is conducted

Netherlands, 

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