Cancer Clinical Trial
Official title:
Vibration Response Imaging (VRI) in Patients That Are Candidates for Undergoing Pulmonary Operation Procedure
The primary objective of this study is to estimate the accuracy of the pre-operative VRI
quantitative results versus the gold standard pre-operative perfusion scan.
The secondary objective is to assess the correlation of the predicted post-operative lung
function with the observed post-operative lung function (forced expiratory volume in 1
second [FEV1] and diffusing capacity of the lung for carbon monoxide [DLCO]) in patients who
underwent surgical resection.
Pre lung operation candidates for procedures such as lung volume reduction surgery (LVRS),
lung resection, bullectomy and lung transplant are frequently evaluated for differential
lung function by a semi quantitative lung scintigraphy. VRI may offer the same differential
lung function information for the physician without the risks, time and patient discomfort
of lung scintigraphy in the treating physician office.
Moreover, VRI may provide a safe, quick and simple method to measure "split function" in
lung cancer patients who are candidates for lung surgery. Thus eliminating the safety and
complexity issue related with the current ventilation perfusion "split function" methods.
In addition the VRI may aid in achieving the goal of developing strategies to reduce risk
and maximize the number of patients that can benefit from surgical therapy.
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Observational Model: Cohort, Time Perspective: Prospective
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