Clinical Trials Logo

Cancer Cachexia clinical trials

View clinical trials related to Cancer Cachexia.

Filter by:

NCT ID: NCT05915325 Recruiting - Cancer Clinical Trials

Physical Training for Elderly Cancer Patients With Cachexia

TEECH-01
Start date: July 5, 2023
Phase: N/A
Study type: Interventional

The goal of the clinical trial is to evaluate the feasibility and efficacy of physical training for elderly cancer patients at risk of cancer cachexia. The main questions it aims to answer are: - Whether a physical training program is feasible in elderly cancer patients with cachexia? - What is the efficacy of a physical training program in reducing the severity of cancer cachexia in elderly cancer patients? Participants will receive a 12-week supervised patient-tailored intensity-modulated physical training and being assessed for the severity of cancer cachexia before and after the training.

NCT ID: NCT05264038 Completed - Cancer Cachexia Clinical Trials

A First in Human Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics Effects of OC514

Start date: March 3, 2022
Phase: Phase 1
Study type: Interventional

Oncocross is developing OC514, a drug-drug combination product containing 2 active pharmaceutical ingredients for cancer cachexia. This study is designed to assess the safety and tolerability of single and multiple oral doses of OC514 in healthy adult volunteers.

NCT ID: NCT05262192 Not yet recruiting - Cancer Cachexia Clinical Trials

Nutrition Education and Quality of Life in Cancer Cachexia

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

With the project the investigators propose, the investigators aim to find answers to the following questions: Are some cachectic factors and cytokines associated with plasma level irisin in patients with advanced stage cancer diagnosed with CACS? Could irisin be a new cachectic factor for patients with CACS? Can providing nutritional education to these patients slow cachexia and can a quality survival be achieved in line with the data obtained from the assessment of quality of life? and the experimental approaches to find answers to these questions make this project unique.

NCT ID: NCT04699760 Completed - Quality of Life Clinical Trials

The Effects of n-3 LCPUFAs in Patients With Colorectal Cancer

Start date: April 2015
Phase: Phase 4
Study type: Interventional

The aim of this study is to determine the effects of n-3 PUFAs on weight, physical funktion and quality of life in patients with colorectal cancer.

NCT ID: NCT04208334 Completed - Clinical trials for Head and Neck Cancer

The Effect of Curcumin for Treatment of Cancer Anorexia-Cachexia Syndrome in Patients With Stage III-IV of Head and Neck Cancer

CurChexia
Start date: February 13, 2020
Phase: Phase 2
Study type: Interventional

A study of Curcumin to prevent cancer anorexia and cachexia Syndrom in locally advance and advance stage head and neck cancer (stage III, IV)

NCT ID: NCT04153019 Completed - Cancer Cachexia Clinical Trials

PSYCHO-EDUCATIONAL AND REHABILITATIVE INTERVENTION FOR CANCER CACHEXIA (PRICC)

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

Half of all cancer patients experience cachexia, with the prevalence rising above 80% in the last weeks of life. The cancer cachexia is a complex relational experience which involves the dyads patients-families. There are no studies on psychosocial interventions on dyads associated with rehabilitative interventions, to support more functional relationships to the management of cancer cachexia. Primary objective: to evaluate the feasibility of a psycho-educational intervention combined with a physiotherapy intervention on the dyads. Secondary objective: improvement of the Quality of Life of dyads, acceptability of the intervention, adherence to each of the two components. Methods: non-pharmacological interventional perspective, mixed-method study, addressed to a consecutive 30 cancer patients with cachexia and irreversible cachexia and their caregivers assisted by Hospital Palliative Care Unit.

NCT ID: NCT04131478 Recruiting - Cancer Cachexia Clinical Trials

Effect of Gene Polymorphisms on the Pathogenesis of Cancer Cachexia

Start date: June 20, 2019
Phase:
Study type: Observational

Cachexia not only directly increases the morbidity and mortality, it also aggravates the side effects of chemotherapy and reduces the overall quality of life that is often considered the major and direct cause of morbidity of a large proportion (>40%) of cancer patients. Individuals with upper gastrointestinal tumors have the highest rate of developing cachexia associated complications. Chemical and physical signals render an environment conducive for disuse and untenable for proper muscle function leading to wasting. Till now, several functional single-nucleotide polymorphisms (SNPs) within TNF-α gene have been identified and described as cancer related genetic alterations.

NCT ID: NCT04127981 Recruiting - Cancer Cachexia Clinical Trials

Medical Imaging of Cachexia

Start date: March 28, 2019
Phase: N/A
Study type: Interventional

This is a pilot trial using 18F-FDG PET and DXA scans to determine whether these investigations are objective tools to assess cachexia.

NCT ID: NCT04067167 Recruiting - Cancer Clinical Trials

Flexi Band Resistance Training Versus EMS Exercise in Patients With the Diagnosis of Malignant Diseases

FREEDOM
Start date: May 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effects of a 12-week flexi band resistance training program compared to different whole-body electromyostimulation (WB-EMS) exercise programs on muscle strength, body composition (in particular muscle mass), cardiorespiratory fitness, inflammation, and patient-reported subjective outcomes (e.g. quality of life, fatigue, performance status) in patients with malignant disease undergoing curative or palliative anti-cancer treatment.

NCT ID: NCT04065815 Recruiting - Cancer Clinical Trials

Protein-rich Nutritional Therapy Combined With Time-efficient Exercise in Cancer Therapy

PROTECT
Start date: May 1, 2019
Phase: N/A
Study type: Interventional

This study aims to evaluate the effects of a 12-week protein-rich individualized nutritional therapy combined with different time-efficient exercise programs on overall physical fitness (cardiorespiratory fitness and muscular fitness), inflammation, and muscle mass/body composition in patients with malignant disease undergoing curative or palliative anti-cancer treatment