Nephrolithiasis Clinical Trial
Official title:
How to Improve Patient Compliance for Metabolic Evaluation and Medical & Dietary Prophylaxis in Calcium Stone Patients?
Calcium oxalate stone, the most common type worldwide, has a recurrence rate of around 50% in
ten years. Therefore, identifying the underlying pathophysiological aspects via metabolic
evaluation and suggestions for medical & dietary prophylaxis in calcium stone patients is of
upmost importance.
However, one of the greatest problem with metabolic evaluation and subsequent therapeutic
advices is the patient compliance. Therefore, it is important to identify factors related to
patient compliance for metabolic evaluation and medical & dietary prophylaxis in calcium
stone patients
Nephrolithiasis is an important health problem that can deteriorate the renal functions in
long term and affects the patients' quality of life. One of the major problems about renal
stones is the high rate of recurrence. Calcium oxalate stone, the most common type worldwide,
has a recurrence rate of around 50% in ten years. Therefore, identifying the underlying
pathophysiological aspects via metabolic evaluation and suggestions for medical & dietary
prophylaxis in calcium stone patients is of upmost importance.
However, one of the greatest problem with metabolic evaluation and subsequent therapeutic
advices is the patient compliance. In the previous studies, even in case of a dedicated stone
clinic, the drop out rate for preventive measures were over 37% per year. The patients'
non-compliance may be related to a number of factors associated with the stone clinic,
demographic characteristics of the patients, past medical history of the patients, and even
the recommended tests and the therapeutic advices.
Therefore, it is important to identify factors related to patient compliance for metabolic
evaluation and medical & dietary prophylaxis in calcium stone patients
Methods:
Parameters to be recorded
Age Gender Level of education
- of stone episodes
- of surgical intervention Type of surgical intervention History of SWL Concomitant
diseases Other medications Type of metabolic evaluation (24 hour urine, spot morning
urine, serum etc.) Drug for medical prophylaxis Dosage of medication (bid/tid, etc.)
Side effects Dietary recommendations Compliance to metabolic evaluation Compliance to
medical treatment
Statistics:
Patients will be grouped based on:
compliance to metabolic evaluation compliance to medical treatment
The parameters listed above will be compared between the groups with univariate analysis
(logistic regression).
;
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