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Cachexia clinical trials

View clinical trials related to Cachexia.

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NCT ID: NCT00081250 Completed - Clinical trials for Unspecified Adult Solid Tumor, Protocol Specific

Creatine in Treating Patients With Cancer-Associated Weight Loss

Start date: December 2004
Phase: Phase 3
Study type: Interventional

RATIONALE: It is not yet known whether the supplement creatine is effective in increasing weight and improving appetite and quality of life in patients who have cancer. PURPOSE: This randomized phase III trial is studying how well creatine works in increasing weight and improving appetite and quality of life in patients with weight loss caused by cancer.

NCT ID: NCT00066248 Completed - Lymphoma Clinical Trials

Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment

Start date: June 2003
Phase: Phase 2
Study type: Interventional

RATIONALE: Cyproheptadine and megestrol may improve appetite and help prevent weight loss in children with cancer. PURPOSE: This phase II trial is studying how well cyproheptadine and megestrol work in improving appetite and preventing weight loss in children with cachexia caused by cancer or cancer treatment.

NCT ID: NCT00060502 Completed - Clinical trials for Pancreatic Neoplasms

A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Pancreatic Cancer Related Cachexia

Start date: April 2003
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effectiveness and safety of infliximab, the active ingredient in Remicade, for the treatment of cachexia in pancreatic cancer patients who are receiving chemotherapy with gemcitabine.

NCT ID: NCT00053053 Completed - Lymphoma Clinical Trials

Comparison of Nutritional Supplements in Preventing Weight Loss in Patients With Cancer

Start date: December 2002
Phase: Phase 3
Study type: Interventional

RATIONALE: Nutritional supplements may help prevent loss of appetite, weight loss, and fatigue in patients with advanced cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two nutritional supplements in preventing loss of appetite, weight loss, and fatigue in patients who have stage III or stage IV solid tumors.

NCT ID: NCT00046904 Completed - Clinical trials for Unspecified Adult Solid Tumor, Protocol Specific

Etanercept in Treating Cancer-Related Cachexia and Anorexia in Patients With Advanced Cancer

Start date: May 2003
Phase: Phase 3
Study type: Interventional

RATIONALE: Etanercept is a substance that is being studied as a treatment for cachexia (weight loss) and anorexia (lack of appetite) in patients who have cancer. It is not yet known whether etanercept is effective in improving cancer-related cachexia and anorexia. PURPOSE: Randomized phase III trial to determine the effectiveness of etanercept in treating cancer-related cachexia and anorexia in patients who have advanced cancer.

NCT ID: NCT00040885 Completed - Lung Cancer Clinical Trials

Docetaxel With or Without Infliximab in Treating Weight Loss, Loss of Appetite, and Fatigue in Patients With Unresectable Non-Small Cell Lung Cancer (Infliximab Treatment Discontinued Effective 10/05/05)

Start date: October 2002
Phase: Phase 3
Study type: Interventional

RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop tumor cells from dividing so they stop growing or die. Infliximab may improve cancer-related weight loss, lack of appetite, and fatigue. It is not yet known whether docetaxel is more effective with or without infliximab in preventing weight loss and fatigue in patients with advanced cancer. (Infliximab treatment discontinued effective 10/05/05) PURPOSE: Randomized phase III trial to determine the effectiveness of docetaxel with or without infliximab in preventing weight loss, loss of appetite, and fatigue in patients who have unresectable non-small cell lung cancer. (Infliximab treatment discontinued effective 10/05/05)

NCT ID: NCT00031785 Completed - Lung Cancer Clinical Trials

Megestrol in Treating Patients Who Are Undergoing Radiation Therapy for Lung Cancer

Start date: September 1, 2000
Phase: Phase 3
Study type: Interventional

RATIONALE: Megestrol helps improve appetite. It is not yet known if megestrol is effective in limiting weight loss in patients who are undergoing radiation therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of megestrol in limiting weight loss in patients who are undergoing radiation therapy for lung cancer.

NCT ID: NCT00031707 Completed - Cachexia Clinical Trials

Comparison of Megestrol and/or Omega-3 Fatty Acid-Enriched Nutritional Supplement in Treating Patients With Cancer-Related Weight Loss and Lack of Appetite

Start date: March 2000
Phase: Phase 3
Study type: Interventional

RATIONALE: Megestrol and /or an omega-3 fatty acid-enriched nutritional supplement may improve cancer-related weight loss and lack of appetite. It is not yet known whether megestrol alone, an omega-3 fatty acid-enriched nutritional supplement alone, or a combination of both is most effective in treating cancer-related weight loss and loss of appetite. PURPOSE: Randomized phase III trial to compare the effectiveness of megestrol with or without an omega-3 fatty acid-enriched nutritional supplement to that of the omega-3 fatty acid-enriched nutritional supplement alone in treating patients who have cancer-related weight loss and lack of appetite.

NCT ID: NCT00028314 Completed - HIV Infections Clinical Trials

Effects of Treatment Changes on Fat Wasting in the Arms and Legs of HIV Patients

Start date: March 2002
Phase: N/A
Study type: Interventional

The goals of this study are to find out if fat wasting and weight loss in the arms and legs of HIV patients taking highly active antiretroviral therapy (HAART) are caused by nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) and if wasting can be reversed if the NRTI is stopped and replaced with other anti-HIV drugs.

NCT ID: NCT00014248 Completed - Clinical trials for Unspecified Adult Solid Tumor, Protocol Specific

Adenosine Triphosphate in Treating Patients With Advanced Solid Tumors

Start date: October 2000
Phase: Phase 1
Study type: Interventional

RATIONALE: Adenosine triphosphate may decrease weight loss and improve muscle strength in patients with advanced solid tumors. PURPOSE: Phase I trial to study the effectiveness of adenosine triphosphate in controlling loss of weight and loss of muscle mass in patients who have advanced solid tumors.