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Clinical Trial Summary

Aim to study efficacy of dexmedetomidine to attenuate hemodynamic response to intubation, skin incision, sternotomy and aortic cannulation


Clinical Trial Description

A randomized controlled trial was conduct between January2024 and March2024 at Sawanpracharak hospital, Thailand. Of 60 patients undergoing elective coronary artery bypass graft, 30 were assigned to group dexmedetomidine and 30 to group control. Dexmedetomidine prepared by anesthetist nurse in concentration 0.1 microgram/kg/ml total volume 50 ml. loading dose 60 ml/hour for 10 minutes before induction of anesthesia then 5ml/hour until the patient on cardiopulmonary bypass (loading dose 1 microgram/kg for 10 minutes then 0.5 microgram/kg/hour). Group control receive normal saline 60ml/hour for 10minutes then 5 ml/hour ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06238011
Study type Interventional
Source Sawanpracharak hospital
Contact Padet Boonmark, MD
Phone +66819927577
Email padet2009@live.com
Status Not yet recruiting
Phase N/A
Start date February 28, 2024
Completion date May 10, 2024

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