Cardiac Surgery Clinical Trial
Official title:
Measurement of Mean Systemic Filling Pressure & Stressed Volume With CardioQ+® Oesophageal Doppler Measurement
To study the reliablity of MSFP and stressed volume to follow volume loading and to predict fload loading responsiveness in patients after elective coronary artery bypass grafting (CABG) surgery.
In this study the oesophageal Doppler monitor (CardioQ+), arterial pulse wave analysis (via
the CardioQ+ and Flotrac device) and central venous pressure (CVP) will be used to estimate
mean systemic filling pressure (MSFP) with the inspiratory hold method. Furthermore the
MSFParm will be determined using a rapid cuff inflator. From MSFP vascular compliance (Csys)
and stressed volume (Vs) will be calculated.
The accuracy of Vs to follow a 500 increase in volume will be studied. The accuracy of MSFP
and Vs to to predict fluid loading responsiveness will be assessed in 42 patients after
elective coronary artery bypass grafting (CABG) surgery. The effect of a standardised fluid
loading on parameters of intrinsic contractility and afterload will be determined. The effect
of fluid loading on inertia, resistance and elastance will be assessed
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