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Bulimia clinical trials

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NCT ID: NCT04057716 Recruiting - Sleep Clinical Trials

Project REST: Regulation of Eating and Sleep Topography

Start date: August 15, 2019
Phase: N/A
Study type: Interventional

Overweight/obesity and inadequate sleep are prevalent, and frequently co-occurring, health risks among children, both of which are associated with serious medical and psychosocial health complications including risk for cardiovascular disease. Although the investigator's data suggest that disrupted or shortened sleep may be causally associated with increased energy intake and weight gain in children, and with self-regulation and neural response to food cues in adults, understanding of mechanisms involved in the sleep/eating association is incomplete, thereby impeding development of targeted, optimally timed intervention strategies. The proposed mechanistic clinical trial aims to assess the effects of an experimental sleep manipulation on eating-related self-regulation and its neural substrates, and on real-world eating behavior, among children with overweight/obesity, which will help guide research efforts towards the refinement of prevention and intervention strategies targeting sleep and its eating-related correlates to curb weight gain throughout development.

NCT ID: NCT04041024 Terminated - Bulimia Nervosa Clinical Trials

Decision-making and Risk-taking in Bulimia

FaciB
Start date: October 28, 2020
Phase: N/A
Study type: Interventional

This trial is a set of four independent experiments involving for each of them functional and structural MRI data acquisition. They aim at investigating decision making mechanisms in bulimia nervosa when participants have to make food or monetary choices under specific conditions that mimic binge eating episodes or kleptomania which are two major symptoms of bulimia nervosa. All experiments are cross sectional studies. Each experiment is subdivided into two parts: a first part without any MRI data acquisition and during which all the tasks are performed. This part aims at making sure that a behavioral effect is observed before starting MRI data acquisition. The second part aims at investigating the neural correlates observed in the first part and additionally, at reproducing the behavioral effects observed in the first part. Therefore the first part may be regarded as an independent study as compared to the second part.

NCT ID: NCT04038190 Recruiting - Depression Clinical Trials

A Behavioral Activation Intervention Administered in a College Freshman Orientation Course

Start date: September 5, 2019
Phase: Phase 2
Study type: Interventional

The transition from high school to college is a developmentally sensitive period that is high risk for escalations in alcohol use. Although risky drinking is a common problem among freshmen, engagement in treatment services is very low. The proposed study will test a behavioral activation intervention that addresses factors limiting participation in standard treatment services by targeting alcohol use indirectly, by directly addressing concerns most relevant to incoming college freshmen, and by integrating an intervention into the college curriculum.

NCT ID: NCT03946540 Active, not recruiting - Anorexia Nervosa Clinical Trials

Longitudinal Follow Up of Eating Disorder Treatment

L-FED
Start date: July 14, 2019
Phase:
Study type: Observational

The research proposed here seeks to delineate the outcomes of people who have received treatment for an eating disorder at a specialist eating disorder service in childhood or adolescence (hereafter 'former patients'). This will inform our understanding of the maintenance of treatment effects beyond initial trial follow-ups, and together with data collected during treatment will allow for identification of factors predicting chronicity which will inform further treatment development.

NCT ID: NCT03946111 Terminated - Obesity Clinical Trials

Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Medication Change for Non-Responders

Start date: August 7, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

This study will test the relative efficacy and effectiveness of the combination of naltrexone and bupropion (NB) medication as a treatment for binge-eating disorder (BED) in patients with obesity. This is a controlled test of whether, amongst non-responders to acute treatments, NB medication results in superior outcomes compared with placebo.

NCT ID: NCT03942874 Completed - Bulimia Nervosa Clinical Trials

Development and Initial Tests of Reward Re-Training: A Novel Treatment For Reward Dysfunction

Recharge
Start date: April 24, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to test a novel treatment for binge eating that will be compared to a waitlist control group. The investigators are seeking to target factors that might influence binge eating by increasing reward in non-food life domains. The treatment is weekly for 10 weeks and will take place at Drexel University in Philadelphia.

NCT ID: NCT03934697 Completed - Anorexia Nervosa Clinical Trials

Imaginal Exposure II Study: In-Vivo

In-vivo IE II
Start date: May 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to test if imaginal exposure therapy can decrease symptoms of eating disorders and anxiety.

NCT ID: NCT03926052 Active, not recruiting - Obesity Clinical Trials

Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Maintenance Treatment

Start date: August 7, 2019
Phase: Phase 3
Study type: Interventional

This study will test the effectiveness of lisdexamfetamine (LDX) medication as a maintenance therapy for the treatment of binge-eating disorder (BED) in patients with obesity. This is a controlled test of whether, amongst responders to acute treatments, LDX medication results in superior maintenance and longer-term outcomes compared with placebo.

NCT ID: NCT03924193 Completed - Obesity Clinical Trials

Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Acute Treatment

Start date: March 25, 2019
Phase: Phase 3
Study type: Interventional

Brief Summary: This study will compare the effectiveness of cognitive behavioral therapy (CBT), lisdexamfetamine (LDX), and the combination of CBT and LDX for the treatment of binge-eating disorder in patients with obesity. This is an acute treatment comparing CBT or LDX alone or in combination.

NCT ID: NCT03855553 Recruiting - Clinical trials for Eating Disorders in Adolescence

Project CORE: Disseminating Eating Disorders Treatment

Start date: January 1, 2019
Phase: Phase 1
Study type: Interventional

The goals of this project are to 1) develop training opportunities for master's-level and pre-doctoral psychology students in evidence-based assessment and treatment of adolescent EDs; 2) to provide the healthcare workforce, including licensed health professionals such as primary care physicians and behavioral health interventionists, with knowledge and competence to recognize early symptoms of and intervention strategies for EDs; and 3) to test the efficacy of delivering two evidence-based treatments for adolescent eating disorders, Family Based Treatment (FBT) and Enhanced Cognitive Behavioral Therapy (CBT-E), in the home-based setting.