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NCT ID: NCT04825158 Not yet recruiting - Clinical trials for Perioperative Complication

Study of the Role of Hemostasis in Perioperative Anaphylaxis

HEMOCANOPE
Start date: April 1, 2021
Phase:
Study type: Observational

Anaphylaxis is a severe and life-threatening complication during the perioperative period. Perioperative anaphylaxis is still associated with a significant mortality despite quick and efficient management using epinephrine, the mainstay of acute treatment. Experimental data and few case reports are suggesting that hemostasis, and more precisely platelets, could play a role in anaphylaxis. Our main hypothesis is that activation of the hemostatic system contributes to the severity of the reaction

NCT ID: NCT04826289 Not yet recruiting - Ankle Fractures Clinical Trials

Vertical Distance Between Medial and Lateral Malleolus in Normal Population

Start date: April 1, 2021
Phase:
Study type: Observational

Determine variation in vertical distance between the medial and lateral malleolus in the normal population subjected to X-rays for any other causes than ankle fracture Determine the effect of weight bearing on this variation

NCT ID: NCT04827043 Not yet recruiting - Clinical trials for Postoperative Analgesia

Quadratus Lumborum Block Versus Thoracic Paravertebral Block

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

This study is to assess and compare the analgesic efficacy and safety of quadratus lumbotum block and paravertebral block in gynacological cancer patients.

NCT ID: NCT04828525 Not yet recruiting - Mastoiditis; Acute Clinical Trials

Corticosteroids as an Additional Treatment for Mastoiditis In Children

COSMIC
Start date: April 1, 2021
Phase: Phase 3
Study type: Interventional

The aim of the study is to assess the influence of adjuvant corticosteroid treatment in acute mastoiditis in children. we expect a better outcome in children treated with both corticosteroids and antibiotics including lower rates in complications and earlier decline in fever and inflammatory markers.

NCT ID: NCT04828759 Not yet recruiting - Aphasia, Acquired Clinical Trials

Virtual Reality in Aphasia Telerehabilitation

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The main purpose of this study is to evaluate the use of the immersive 3D HMD VR technology in the language intervention with a home-based telerehabilitation approach for people with aphasia. The assessments will be conducted at the baseline (prior the intervention periods) and after each intervention period (i.e. after the VR-intervention period and the waitlist period).

NCT ID: NCT04832191 Not yet recruiting - Breast Neoplasms Clinical Trials

CE-MRI&CESM in Solid Breast Lesions

Start date: April 1, 2021
Phase:
Study type: Observational

Our study aimed to assess the accuracy of CE-SM in comparison to contrast-enhanced breast MRI in the evaluation of solid breast lesions.

NCT ID: NCT04833530 Not yet recruiting - Ultrasonography Clinical Trials

The Effect of Preoperative Anxiety, on Gastric Antrum Size in Women Undergoing in Vitro Fertilization

Start date: April 1, 2021
Phase:
Study type: Observational

Pulmonary aspiration is one of the most serious risks of general anesthesia and has been reported to occur in as many as 1 in 4000 cases of general anesthesia. Gastric ultrasound is an emerging point-of-care tool that provides bedside information on gastric content and volume. There have been a few factors which are thought to increase gastric size. Delayed gastric emptying such as caused by gastroparesis in Diabetes Mellitus is an example. Certain surgeries also cause gastroparesis. Other preoperative factors including pain, preoperative anxiety, and blood levels of estradiol or progesterone are less well studied.

NCT ID: NCT04835064 Not yet recruiting - Clinical trials for Pancreatic Adenocarcinoma

Pancreatic Cancer With Elevated Serum CA125 Were Compared With Those Who Did Not Receive Neoadjuvant Chemotherapy.

Start date: April 1, 2021
Phase: Phase 3
Study type: Interventional

The main purpose of - To observe the overall survival of patients with resectable pancreatic cancer with elevated serum CA125 with and without neoadjuvant chemotherapy A secondary purpose - To observe relapse-free survival in patients with resectable pancreatic cancer with elevated serum CA125 versus without neoadjuvant chemotherapy - To observe the resectable rate of patients with resectable pancreatic cancer with elevated serum CA125 with and without neoadjuvant chemotherapy - To observe the safety parameters of patients with resectable pancreatic cancer with or without neoadjuvant chemotherapy with elevated serum CA125

NCT ID: NCT04835181 Not yet recruiting - Obesity, Abdominal Clinical Trials

Electroacupuncture Combined With Umbilical Moxibustion on Abdominal Obesity of Yang Deficiency

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

Obesity is a chronic metabolic disease that seriously harms human health, while abdominal obesity is more closely related to diseases such as type 2 diabetes, cardiovascular disease, and tumors, and has a higher risk. In recent years, traditional Chinese medicine therapy has become the choice of more and more obese patients, and acupuncture therapy is also known as a green therapy for weight loss due to its safety and no side effects. Through the analysis of the TCM physique types of obese people, it is found that Yang-deficiency constitution is one of the TCM constitution types closely related to simple obesity. This topic is based on the constitution theory of traditional Chinese medicine, and on the basis of the earlier research that has clarified the weight loss and lipid-lowering effects of electroacupuncture, it further aims at the type of yang deficiency in obese people, and clarifies the regulation and improvement of umbilical moxibustion on the constitution of obese patients with yang deficiency. In this project, patients with abdominal obesity with yang-deficiency constitution were divided into electro-acupuncture + umbilical moxibustion group and electro-acupuncture group to observe and analyze the advantages and effects of electro-acupuncture combined with umbilical moxibustion on the improvement of obesity symptoms and physical fitness of patients. The ELISA method was used to determine the metabolic indexes related to yang-deficiency constitution, to further clarify the material basis of electroacupuncture combined with umbilical moxibustion to improve the yang-deficiency constitution of patients with abdominal obesity, and to provide scientific and reasonable theoretical guidance for clinical treatment.

NCT ID: NCT04836728 Not yet recruiting - Clinical trials for Non-small Cell Lung Cancer Metastatic

Study of Chemotherapy and PD-1 Inhibitor Combination With Autologous CIK Cell Immunotherapy to Treat Lung Cancer

CCICC-002b
Start date: April 1, 2021
Phase: Phase 2
Study type: Interventional

This prospective,multicenter, open-labe phase II study is to evaluate the effects of autologous cytokine-induced killer cell immunotherapy combination with PD-1 inhibitor and chemotherapy in the first-line treatment of IV non-small cell lung cancer.