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NCT ID: NCT04300543 Not yet recruiting - Multiple Sclerosis Clinical Trials

MicroRNA-150 and microRNA-155 in Multiple Sclerosis

Start date: April 2020
Phase:
Study type: Observational

A study To analyse the expression of circulating miR-150 and miR-155 in serum of MS patients, Evaluate the serum levels of oligoclonal bands, neurofilaments and chitinase-3-like-1 in serum of MS patients, and Investigate the correlation between the measured biomarkers and each other and their correlation with different MS phenotypes , disability status and the patients demographic data.

NCT ID: NCT04301817 Not yet recruiting - Clinical trials for Optic Nerve Sheath Diameter

Changes in Optic Nerve Sheath Diameter in Patients Undergoing Spinal Surgery in the Prone Position

Start date: April 2020
Phase:
Study type: Observational

Long standing prone position could affect vision or optic nerve. To measure the optic nerve sheath diameter using ultrasound is quick and useful assessments of patients. This study will look at the change of optic nerve sheath diameters of patients undergoing surgery in prone position

NCT ID: NCT04301830 Not yet recruiting - Clinical trials for Intracranial Hypotension

Postoperative Changes in Optic Nerve Sheath Diameter in Patients Undergoing Spinal Anesthesia for Cesarean Delivery

Start date: April 2020
Phase:
Study type: Observational

This is observational study. The investigator will measure optic nerve sheath diameter by ultrasound on the eye after cesarean section under spinal anesthesia.

NCT ID: NCT04303351 Not yet recruiting - Clinical trials for Atherosclerosis of Artery

Periodontitis and Atherosclerotic-related Arterial Stenosis

Start date: April 2020
Phase:
Study type: Observational

This study aimed to evaluate the association between periodontitis and atherosclerosis of the cerebral vasculature in the Chinese population.

NCT ID: NCT04306913 Not yet recruiting - Clinical trials for Cardioplegia Solution Adverse Reaction

Outcome of Esmolol Potassium Cardioplegia Compared to Potassium Cardioplegia in Patients With Solitary Valvular Disease; Randomized Controlled Study

Start date: April 2020
Phase: N/A
Study type: Interventional

Perioperative myocardial injury remains one of the most serious complications of cardiac surgery. Numerous factors have been implicated during the pathogenesis process, including the technique of cardiac surgery, induction of cardioplegia and period of cardiac arrest. Lactic acid is the normal endpoint of the anaerobic breakdown of glucose in the tissues. The lactate exits the cells and is transported to the liver, thus it's considered to be an indicator of ischemia as it is produced by most tissues in the human body, with the highest level of production found in muscle. In any cardiac valve replacement surgery, patient must undergo cardiac bypass and arrest in diastole by using hyperkalemic cardioplegia solution; meanwhile the metabolism of myocardial cells is purely anaerobic. Esmolol an ultra-short beta blocker is supposed to decrease the anaerobic insult to the myocardial cells.

NCT ID: NCT04307888 Not yet recruiting - Clinical trials for Aortic Valve Stenosis

Spanish Percutaneous Aortic INtervention REGISTRY (SPAIN REGISTRY)

SPAIN
Start date: April 2020
Phase:
Study type: Observational [Patient Registry]

Multicentre prospective registry including consecutive patients undergoing Percutaneous Endovascular Aneurysm Repair (PEVAR), Percutaneous Endovascular Thoracic Aneurysm Repair (PTEVAR) or Transcatheter Aortic Valve Implantation (TAVI) in which variables related to the percutaneous access closure for implanting devices at aorta level will be collected and analyzed. The follow-up period will be 30 days after the procedure. The duration of the recruitment period will be one year. All data will be collected telematically and incorporated into a database for subsequent statistical analysis. There will be 2 points for data interim analysis at 6 and 12 months after initiation of the study.

NCT ID: NCT04309175 Not yet recruiting - Blood Pressure Clinical Trials

Long-term Atrial Pacing and Central Blood Pressure

Start date: April 2020
Phase: N/A
Study type: Interventional

This is a randomized controlled single-centre clinical trial with a cross-over design to compare non-invasively evaluated central blood pressure and related parametres in sick sinus syndrome patients with hypertension who are paced long-term at a slower vs faster heart rate

NCT ID: NCT04312620 Not yet recruiting - ILM Peeling Clinical Trials

Evaluation of OCT and Visual Field Changes After Vitrectomy and ILM Peeling

Start date: April 2020
Phase:
Study type: Observational

To evulate changes in VF and OCT after viterctomy associated with ILM peeling.

NCT ID: NCT04313660 Not yet recruiting - NSCLC Clinical Trials

Anlotinib In Combination With PD-1/L1 Inhibitor As Sequential Therapy of Thoracic Radiotherapy After Induction Chemotherapy For Extensive-Stage Small Cell Lung Cancer:A Single Arm Study

Start date: April 2020
Phase: Phase 2
Study type: Interventional

Anlotinib In Combination With PD-1/L1 Inhibitor As Sequential Therapy of Thoracic Radiotherapy After Induction Chemotherapy For Extensive-Stage Small Cell Lung Cancer:A Single Arm Study

NCT ID: NCT04314063 Not yet recruiting - Food Borne Diseases Clinical Trials

Knowledge,Attitude and Practice of Food Handleres About Food Safety

Start date: April 2020
Phase:
Study type: Observational

The heavy burden of food borne diseases causes substantial economic losses to individual , households, health systems and entire nations. As poor food hygienic practices could contribute food -borne diseases in hospital, so food handlers' knowledge, attitude and practicing is an important factor that is essential in order to lower food borne disease. All three traits; knowledge, attitude and education are compulsory to enable safe food handling practices