There are more than 498,563 clinical trials published worldwide with over 60,000 trials that are currently either recruiting or not yet recruiting. Use our filters on this page to find more information on current clinical trials or past clinical trials (free or paid) for study purposes and read about their results.
The aim of the study is to compare the efficacy and safety of low-dose combination of three antihypertensive drugs versus fixed high-dose combination of two antihypertensive drugs in arterial hypertension
Class III malocclusions may originate in a retrognathic maxilla, a prognathic mandible or both. Young patients with class III malocclusion and maxillary hypoplasia are conventionally treated with a protraction facemask in order to stimulate forward growth of the upper jaw. This treatment option is often inducing unwanted side effects including mesial migration of the teeth in the upper jaw and clockwise rotation of the mandible. Because skeletal effects are often difficult to achieve with this approach, more pronounced class III malocclusions cannot be addressed by face mask therapy. These children cannot be treated during childhood and end up in major orthognathic surgery at full-grown age. To be able to treat also the more pronounced class III malocclusion and to minimize dentoalveolar compensations new treatment methods were developed which uses skeletal anchorage.
The aim of the study is to compare orbital and central nervous system (CNS) imaging with Computed Tomography (CT) scan to that of Fast Magnetic Resonance Imaging (Fast MRI) in children with mild, moderate or severe orbital cellulitis with medical indications for imaging.
Lycra garments have recently been used for children with cerebral palsy, with favorable effects on alignment, biomechanics and neuromuscular activity. The aim of the present study is to determine the efficacy of a Lycra suit in improving motor function and static balance in children with cerebral palsy. The children included in this study will be part of a prospective project on children with cerebral palsy, older than 4 years of age, and their families regularly followed at the Child Neurology Unit of the Catholic University of Rome.
This study will determine the effect of the wireless micro current stimulation in pediatric deep dermal burns and scald injuries. The clinical trial ist designed as a blinded, placebo-controlled, randomized, prospective, single-center study.
Compared with breast milk and another commercially available formula, infants' growth rate after 12 weeks' Friso formula with different ways of processing feeding will be assessed.
The purpose of this study is to examine the efficacy of mid-infrared spectroscopy together with Attenuated Total Reflection (ATR), for the detection of gynecological malignancies in real time during surgery.
Prospective randomized clinical trial to assess the effect of in-hospital intensive counseling and follow-up vs. usual care, on re-admission rates of patients with Asthma. The study population will include asthma patients admitted to internal Medicine departments and medical ICU at Soroka University Medical Center, due to asthma exacerbation.
The main goal of this study is to employ a novel proteomic approach to identify predictive tumor biomarkers that will increase the efficacy of insulin-like growth factor (IGF1R) targeted therapy in epithelial ovarian cancer. It is expected that these predictive biomarkers will be applied to increase the response rate in selected groups of patients.
Suicide is the 2nd leading cause of death for teenage youth in Canada, and every year tens of thousands of young people engage in suicidal behaviors. Many young people manifest red-flag behaviors in the digital realm before these incidents occur. The faceless nature of online communication often emboldens youth to reveal details about their mental state: leaving tell-tale signs or "bread crumbs" of their suicidal intentions or behaviors. This research will examine the content of adolescents social media entries to find red flags and detect patterns in social media interactions of adolescents that could be predictive of subsequent suicide risk. The study participants will be patients admitted to Child and Adolescent Psychiatry Emergency unit at BCCH, subdivided into two groups: those admitted due to suicidal behaviors, and those admitted for non-suicidal behaviors. The text of social media activity for the month prior to emergency admission of the two groups will be collected, anonymized, and analyzed using text-analytic algorithms. The objective of the study is to find patterns and indicators of social media entries, prior to admission, that would have been predictive of suicidality. The implications of successful outcome of this project for mental health care of children and adolescents reaches well beyond the scope of this study. An objective method to predict risk of suicidal behaviors in youth has application in almost all pediatric clinical settings. The outcomes of this project will also serve as the foundation for further utilization of social sensing technology to identify, predict, and prevent many other mental health crises in children and adolescents.