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NCT ID: NCT00130897 Approved for marketing - Clinical trials for Carcinoma, Renal Cell

Treatment Use Study With Sunitinib (SU011248) For Patients With Cytokine-Refractory Metastatic Renal Cell Carcinoma

Start date: July 2005
Phase: N/A
Study type: Expanded Access

The primary objective of this protocol is to provide access to SU011248 treatment for patients with metastatic RCC who are ineligible for participation in ongoing SU011248 clinical studies and have the potential to derive clinical benefit from treatment with SU011248 based on the judgment of the investigator.

NCT ID: NCT00338247 Approved for marketing - Neoplasms, Breast Clinical Trials

EAP (Expanded Access Protocol) Of Lapatinib Combined With Capecitabine In Metastatic Breast Cancer

Start date: July 2006
Phase: Phase 4
Study type: Expanded Access

This study will provide pre-approval drug access to lapatinib, in combination with capecitabine, to patients whose breast cancer had progressed on other therapies

NCT ID: NCT01160250 Approved for marketing - Clinical trials for Basal Cell Carcinoma

A Study of Vismodegib (GDC-0449) in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma

Start date: July 2010
Phase: Phase 4
Study type: Expanded Access

This is an open-label, non-comparative, multicenter, expanded access study of Vismodegib (GDC-0449) in patients with locally advanced basal cell carcinoma (BCC) or metastatic BCC (mBCC) who are otherwise without satisfactory treatment options.

NCT ID: NCT01649284 Approved for marketing - Clinical trials for Carcinoma, Non-Small-Cell Lung

Afatinib Expanded Access Program

Start date: July 2012
Phase: N/A
Study type: Expanded Access

This is an open-label, multi-center, single-arm trial, designed to provide early access to afatinib and to provide additional information on the safety and efficacy of afatinib in advanced NSCLC patients who harbor an EGFR mutation.

NCT ID: NCT00918424 Approved for marketing - Epilepsy Clinical Trials

Long Term Study of the Safety of OXC XR as in Pediatric Epilepsy Subjects

Start date: June 2009
Phase: N/A
Study type: Expanded Access

Follow-on study to continue evaluation of the safety of OXC XR as adjunctive therapy in pediatric epilepsy

NCT ID: NCT00293098 Approved for marketing - Iron Overload Clinical Trials

Compassionate Use of Deferiprone for Patients With Thalassemia and Iron-Induced Heart Disease

Start date: March 2006
Phase: N/A
Study type: Expanded Access

Patients who have iron overload due to chronic blood transfusions and have developed heart failure or who are at high risk of heart failure because of the high levels of iron in their hearts, will be treated with deferiprone, an investigational drug, in combination with deferoxamine (Desferal). Some studies suggest that deferiprone may be better than deferoxamine in removing iron from the heart and improving heart function, and that using both drugs together may remove more iron. Participants would make a clinic visit for lab studies each week, and would continue to take deferiprone for as long as their physician feels it is useful in their care.

NCT ID: NCT00733447 Approved for marketing - Clinical trials for Biventricular Failure

SynCardia Freedom Driver System Study

Start date: March 2010
Phase: N/A
Study type: Expanded Access

The purposes of this study are to confirm that the Freedom Driver System is a suitable pneumatic driver for clinically stable TAH-t subjects, and that patients and lay caregivers can be trained to manage the Freedom Driver System safely outside the hospital.

NCT ID: NCT01240421 Approved for marketing - Clinical trials for Metastatic Breast Cancer

An Open-Label, Multi-Center, Expanded Access Program With Eribulin for the Treatment of Advanced Breast Cancer Refractory

Start date: March 2011
Phase: N/A
Study type: Expanded Access

This expanded access program is an open-label, multi-center study, which will consist of a PreTreatment Phase and a Treatment Phase. Patients with locally advanced or metastatic breast cancer who fulfill the eligibility criteria will be treated. The program will continue in each country until eribulin is approved, reimbursed and launched in that country, or termination of the program by the Sponsor.

NCT ID: NCT00062660 Approved for marketing - HIV Infections Clinical Trials

Tipranavir in Patients With Progressive, Systemic HIV-1 Disease Who Have Failed or Are Intolerant to Currently Approved Treatments for HIV Infection

Start date: May 2003
Phase: N/A
Study type: Expanded Access

To provide early access to tipranavir and evaluate the safety and tolerance of tipranavir combined with low dose of ritonavir in patients with progressive, HIV-1 disease who have failed or are intolerant to currently approved treatments for HIV infection, who are unable to participate in another tipranavir controlled clinical trial and have an urgent need for anti-HIV treatment.

NCT ID: NCT00933205 Approved for marketing - HIV Infections Clinical Trials

An Open Label Safety Study of Tipranavir Co-administered With Low-dose Ritonavir in Patients With Advanced HIV-1 Infection and Limited Treatment Options.

Start date: May 2004
Phase: N/A
Study type: Expanded Access

The purpose of this Open Label Safety Study is to provide access to and evaluate the safety and tolerability of TPV/r in treatment-experienced patients with advanced HIV-1 infection who have failed at least two PI-containing regimens, and have limited treatment options.