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NCT ID: NCT04333394 Not yet recruiting - Clinical trials for Attention Deficit Hyperactivity Disorder

Effectiveness of Probiotic Supplement In Improving Attention Deficit Hyperactivity Disorder Symptoms

Start date: April 20, 2020
Phase: N/A
Study type: Interventional

To study the effects of probiotic supplement in children with Attention-deficit hyperactivity disorder (ADHD),40 patients will be randomly allocated to two groups of intervention and placebo. The intervention and the placebo group will be prescribed with 1 capsule of probiotics and placebo for 8 weeks, respectively. Treatment efficacy will be assessed via administrating the Conners's rating

NCT ID: NCT04344132 Not yet recruiting - Clinical trials for Supratentorial Neoplasms

Pre- vs. Postoperative Scalp Block for Pain Control After Supratentorial Craniotomy

Start date: April 20, 2020
Phase: N/A
Study type: Interventional

Study was designed to evaluate optimal timing for selective scalp block in patients undergoing general anesthesia for supratentorial craniotomy.Pain score assessed by visual analog scale (VAS) preoperatively (baseline) and after extubation at 2, 6, 12 and 24 hours; time first request of a patient for rescue analgesia; intraoperative anesthetics and opioids consumption; awakening time; perioperative complications.

NCT ID: NCT04344756 Not yet recruiting - COVID19 Pneumonia Clinical Trials

Trial Evaluating Efficacy and Safety of Anticoagulation in Patients With COVID-19 Infection, Nested in the Corimmuno-19 Cohort

CORIMMUNO-COAG
Start date: April 20, 2020
Phase: Phase 2
Study type: Interventional

COVID-19 is a respiratory disease caused by a novel coronavirus (SARS-CoV-2) and causes substantial morbidity and mortality. There is currently no vaccine to prevent Covid-19 or infection with SARS-CoV-2 or therapeutic agent to treat COVID-19. This protocol CORIMUNO19-COAG will evaluate the efficacy and safety of active anticoagulation using heparin: Tinzaparin (INNOHEP®) or unfractionated heparin (Calciparine®, Héparine Sodique Choay®) in COVID-19 patients hospitalized in conventional or intensive care units. It will use a phase 2 randomized open-label multicentre clinical trial, where patients will be randomly allocated to anticoagulation versus Standard of Care.

NCT ID: NCT04346043 Not yet recruiting - Clinical trials for Coronavirus Disease (COVID-19)

To Access the Egyptian COVID-19 Whole Genome by NGS and Compare to the International Worldwide Database

Strain
Start date: April 20, 2020
Phase:
Study type: Observational

This is an exploratory study that will be performed on confirmed positive COVID-19 samples to identify the dominant viral genome strain in Egyptians using next generation sequencing (NGS).

NCT ID: NCT04348877 Not yet recruiting - Clinical trials for Coronavirus Disease (COVID-19)

Plasma Rich Antibodies From Recovered Patients From COVID19

PRA-001
Start date: April 20, 2020
Phase: N/A
Study type: Interventional

Prospective interventional study, single arm of purified convalescent plasma transfusion as an add on therapy for the standard of care treatment (national guideline) (Oseltamivir (75mg/12 hours for 5-10 days) and hydroxychroquine (400mg twice in first day, 200 twice for 4-9 days) ± Azithromycin 500mg daily for 5 days

NCT ID: NCT04350931 Not yet recruiting - Clinical trials for Coronavirus Disease (COVID-19)

Application of BCG Vaccine for Immune-prophylaxis Among Egyptian Healthcare Workers During the Pandemic of COVID-19

Start date: April 20, 2020
Phase: Phase 3
Study type: Interventional

Phase III Placebo-controlled adaptive multi-centre randomized controlled trial Interventional (Clinical Trial). The study will include nine hundred healthcare workers in the isolation hospitals for COVID-19 cases; they will be randomly assigned to receive either BCG vaccine or normal saline.

NCT ID: NCT04355884 Not yet recruiting - COVID-19 Clinical Trials

Opportunistic Screening for Asymptomatic Left Ventricular Dysfunction in Coronavirus Disease 2019 (COVID19) Survivors

Start date: April 20, 2020
Phase:
Study type: Observational

Coronavirus Disease 2019 (COVID-19) emerged in December 2019, and in mere few months has resulted in a pandemic of viral pneumonia. Substantial proportion of patients with COVID-19 have biochemical evidence of myocardial injuries during the acute phase. Possible mechanisms including acute coronary events, cytokine storm, and COVID-19 related myocarditis, have been postulated for the cardiac involvement in COVID-19. It is uncertain whether COVID-19 survivors are at risk cardiac dysfunction including cardiac arrhythmia and heart failure. The prospective screening study aims to evaluate the possible latent effects from COVID-19 in COVID-19 survivors. COVID-19 survivors 4-6 weeks after hospital discharge will be recruited from the Infectious Disease clinic, Queen Mary Hospital with standard 12-lead electrocardiogram, serum troponin, NT-proBNP, and standard transthoracic echocardiogram. The outcome measures include (1) new onset cardiac arrhythmia, (2) N Terminal (NT)-proBNP elevation above the diagnostic range of heart failure, and (3) newly detected left ventricular dysfunction.

NCT ID: NCT04359316 Not yet recruiting - COVID-19 Clinical Trials

Azithromycin in Hospitalized COVID-19 Patients

AIC
Start date: April 20, 2020
Phase: Phase 4
Study type: Interventional

The present study is a randomized, double-blind, controlled, clinical trial, with the approval of the ethics committee will be conducted on patients who have a positive test confirming COVID-19 in Shahid Modarres Medical Education Center and Hospital in Tehran. Patients will be randomly assigned to the two arms of the study and after completing the course of treatment and collecting and analyzing the necessary information from each patient, the results of the study will be published both on this site and in the form of an article in a reputable international journal.

NCT ID: NCT04359615 Not yet recruiting - COVID-19 Clinical Trials

Favipiravir in Hospitalized COVID-19 Patients

FIC
Start date: April 20, 2020
Phase: Phase 4
Study type: Interventional

The present study is a randomized, double-blind, controlled, clinical trial, with the approval of the ethics committee will be conducted on patients who have a positive test confirming COVID-19 in Shahid Modarres Medical Education Center and Hospital in Tehran. Patients will be randomly assigned to the two arms of the study and after completing the course of treatment and collecting and analyzing the necessary information from each patient, the results of the study will be published both on this site and in the form of an article in a reputable international journal.

NCT ID: NCT04806581 Not yet recruiting - Liver Cirrhosis Clinical Trials

Clinical Study of Hepatocyte Transplantation for Liver Cirrhosis

Start date: April 20, 2021
Phase: Phase 1
Study type: Interventional

The Primary Objective: To observe and determine the safety and tolerance of allogeneic hepatocyte transplantation in patients with liver cirrhosis and to establish the maximum-tolerated dose (MTD) and evaluate the dose-limiting toxicities (DLTs). The Secondary Objective: To observe the therapeutic efficacy of allogeneic hepatocyte transplantation for liver cirrhosis.