Breast Neoplasms Clinical Trial
Official title:
A Phase I/II, Open-Label, Multicenter Study to Investigate the Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of DZD3969 as Monotherapy or in Combination With Palbociclib in Postmenopausal Female Patients With Estrogen Receptor Positive (ER+) and HER2 Negative (HER2-) Breast Cancer
This study will treat patients with advanced ER+HER2- breast cancer who have progressed following prior therapy. This is the first time this drug has ever been tested in patients, and so it will help to understand what type of side effects may occur with this new drug. It will also measure the levels of drug in the body and preliminarily assess its anti-cancer activity as alone and in combination with Palbociclib
A Phase I/II, Open-Label, Multicenter Study to Investigate the Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of DZD3969 as Monotherapy or in Combination with Palbociclib in Postmenopausal Female Patients with ER+ HER2- Breast Cancer. This study includes dose escalation part, dose expansion part and combination expansion part. ;
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