Prevention of Female Cancers by Optimization of Selenium Levels in the Organism. — SELINA  

Breast Neoplasms Clinical Trial

Official title: Prevention of Females Malignancies in Families With Hereditary Breast Cancer by Personalized Optimization of Se Levels in the Organism.

Status Active, not recruiting

Clinical Trial Summary

Hypothesis to be tested:

Oral supplementation or diet modifications of selenium to a specified range will be effective in reducing the risk of developing cancer of any type in women with high risk of breast cancer, as compared to placebo.

Clinical Trial Description

Primary Objective

• To determine the efficacy of oral daily supplementation or diet modification of selenium to an optimal level compared to placebo, in reducing the incidence of any cancers in an at risk population of women over the 60 months of the study.

Secondary Objectives

• To determine the efficacy of oral daily supplementation or diet modification of selenium to an optimal level compared to placebo, in reducing the incidence of breast cancer in an at risk population of women over the 60 months of the study.

• To explore the relationship between the effects of study supplement or diet modifications on cancer risk and genetic factors.

The study will have 7000 participants. All the measurements will be performed via blood tests. ;

Related Conditions & MeSH terms

• Breast Neoplasms

• NCT number: NCT04014283
• Study type: Interventional
• Source: Read-Gene S.A.
• Status: Active, not recruiting
• Phase: N/A
• Start date: October 2014
• Completion date: November 2023