Breast Neoplasms Clinical Trial
Official title:
Association Between Genetic Polymorphisms of CYP2D6 and Outcomes in Breast Cancer Patients With Tamoxifen Treatment
The genetic polymorphisms of the cytochrome P450 may influence on the metabolism of
tamoxifen.
The investigators want to
- evaluate the frequency or incidence of the genetic polymorphisms of cytochrome P450
subfamilies(CYP2D6, CYP3A4/5 and CYP2C19) in breast cancer patients, and
- analyze the association between the genetic polymorphisms of cytochrome P450
subfamilies and clinical outcomes in breast cancer patients treated by adjuvant
tamoxifen therapy.
n/a
Observational Model: Cohort, Time Perspective: Retrospective
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