Deep Inferior Epigastric Artery Flap for Breast Reconstruction

Breast Cancer Clinical Trial

Official title:

Division of Plastic and Reconstruction Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05088239
• Other study ID #: CYCH-IRB No.2020092
• Status: Completed
• Start date: July 1, 2011
• Est. completion date: December 31, 2020

Study information

• Verified date: October 2021
• Source: Chiayi Christian Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Background: There is no consensus on the duration of prophylactic antibiotics for autologous breast reconstruction after mastectomy. We try to standardize prophylactic antibiotics use during breast reconstruction with deep inferior epigastric perforator flap following mastectomy. Methods: This retrospective case series involved 108 patients who underwent immediate breast reconstruction with deep inferior epigastric perforator flap in Ditmanson Medical Foundation Chia-Yi Christian Hospital between 2012 and 2019. Patients were divided into three groups based on prophylactic antibiotic duration: 1 day, 3 days and >7 days for patients with drains Data were analyzed between January and April, 2021.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 108
• Est. completion date: December 31, 2020
• Est. primary completion date: December 31, 2019
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 24 Years to 63 Years

Eligibility

Inclusion Criteria:

• This retrospective study involved 108 patients who underwent immediate DIEP flap breast reconstruction after unilateral or bilateral mastectomy at the Ditmanson Medical Foundation Chia-Yi Christian Hospital between 2012 and 2019.

Exclusion Criteria:

• Age < 20 years old.

Related Conditions & MeSH terms

• Anti-Infectives Adverse Reaction
• Breast Cancer
• Infections

Intervention

Drug:
• prophylactic antibiotics duration
Prophylactic cefazolin 1000 mg was given 30 minutes before surgery, every 4 hours in the peri-operative period, and every 6 hours in the post-operative care. Different discontinued duration of antibiotics was divided to 3 groups in one day, 3 days and until to drain removal.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Chiayi Christian Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	surgical site infection (SSI)	Infection rate of surgical wounds of breast and abdomen.	Patients were then followed up in the outpatient department for 1 year.