Use of Compressed Sensing in Breast MRI

Breast Cancer Clinical Trial

— COMPRIM  

Official title:

Use of Compressed Sensing in Breast MRI

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02826369
• Other study ID #: 2015-A00581-48
• Status: Completed
• Phase: N/A
• Start date: March 29, 2016
• Est. completion date: April 12, 2016

Study information

• Verified date: August 2018
• Source: Institut de Cancérologie de Lorraine
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Breast MRI is increasingly important in breast screening imaging. It is currently based on dynamic sequences after contrast injection whose temporal resolution must be less than 90 seconds with dynamic acquisitions at different times.

These curves profiles are designed to differentiate benign from malignant lesions. Recently, Mann et al, (2014) showed that increasing the temporal resolution of dynamic acquisitions; lesion enhancement curves over time were more accurate than the curves usually performed.

It seems necessary to work on sequences having better temporal resolution without compromising however spatial resolution.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 13
• Est. completion date: April 12, 2016
• Est. primary completion date: April 12, 2016
• Accepts healthy volunteers: No
• Gender: Female
• Age group: N/A to 18 Years

Eligibility

Inclusion Criteria:

• Patient to benefit a MRI in the assessment for a breast carcinoma

• Age >18 years old

• Assessment on 3.0 Tesla in Magnetic Resonance Imaging

• ECOG performance status = 3

• Ability to provide an informed written consent form

Exclusion Criteria:

• Age < 18 years old

• Claustrophobia

• Contraindication to the injection of gadolinium contrast medium

• Contraindication to MRI

• Persons deprived of liberty or under supervision

Related Conditions & MeSH terms

• Breast Cancer

Intervention

Other:
• 3.0 Tesla in Magnetic Resonance Imaging
Eligible patient will have a standard MRI. The images taken before 4min30 and after 6min after to the injection of gadolimium contrast medium will be carried out with the standard image acquisition. The images taken between 4min30 and 6min after the injection of gadolimium contrast medium will be carried out with the compressed sensing image acquisition.

Locations

Country	Name	City	State
France	Institut de Cancérologie de Lorraine	Vandoeuvre-Lès -Nancy

Sponsors (1)

Lead Sponsor	Collaborator
Institut de Cancérologie de Lorraine

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Agreement between compressed sensing and standard image acquisition	Agreement between compressed sensing and standard image acquisition is defined by percentage of lesions detected by both modes of acquisitions	1 day
Secondary	Analysis of dammage contours	Analysis of lesions contours will be performed according to Bi-RADS classification	1 day
Secondary	Image quality in compressed sensing acquisition	The image quality will be evaluated using a quality scale	1 day