Breast Cancer Clinical Trial
Official title:
Performance of Tc99m Sestamibi Molecular Breast Imaging (Tc-MBI) Versus Magnetic Resonance Imaging in the Diagnosis of Breast Carcinoma: A Pilot Study
The objective of this study is to evaluate the usefulness of Tc-99m Sestamibi Molecular
Breast Imaging as an imaging modality for breast cancer screening.
Tc-MBI has shown significantly higher sensitivity and equivalent specificity in the
detection of breast cancer among high risk women when compared to mammography. However,
there is little published data comparing Tc-MBI to MRI for evaluating extent of disease in
women with known breast cancer.
The study will target twenty (20) women with newly diagnosed breast cancer who are scheduled
to undergo biopsy of additional suspicious lesions that were identified on standard of care
contrast- enhanced breast MRI. Prior to the biopsy, these subjects will receive a Tc-MBI
scan of the breast. The results from both imaging methods will be compared to histological
findings. These results may be used to design larger and more comprehensive studies with an
overarching goal to determine if there is a role for Tc-MBI in the pre-operative evaluation
of patients with known breast cancer.
n/a
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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