Multiple Oncological Serial Scans Study — MOSS  

Breast Cancer Clinical Trial

Official title: The Tumour Bed as Target for Breast Irradiation Following Breast Conserving Surgery

Status Terminated

Clinical Trial Summary

This is a pilot study comparing the appearance and volume of the post surgical region in the intact breast, as determined by 3 modalities: computed Xray tomography (CT), 3 Dimensional ultrasound (USS), Magnetic resonance imaging (MRI) after breast conserving surgery and during whole breast irradiation.

Clinical Trial Description

Consenting patients who have undergone breast conserving surgery and who are planned to receive radiotherapy will have their first MRI and CT scan within 2 weeks of treatment planning. This will be followed by 3 weeks radiotherapy treatment. 3D ultrasound scans will be performed in the first 2 weeks before radiotherapy, during the 2nd and 3rd weeks of radiotherapy and in the 2 weeks following radiotherapy.Following the radiotherapy patients will undergo both CT and MRI scans within 2 weeks of treatment completion.The whole process should take approximately 10 weeks.In this study the CT scans, MRI scan + USS are above standard care and are the additional interventions in this study group. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label

Related Conditions & MeSH terms

• Breast Cancer

• NCT number: NCT01246726
• Study type: Interventional
• Source: University Hospitals Bristol NHS Foundation Trust
• Status: Terminated
• Phase: N/A
• Start date: November 2010
• Completion date: March 2013