MRI in Assessing Tumor Size in Women With Ductal Carcinoma In Situ

Breast Cancer Clinical Trial

Official title: Ductal Carcinoma in Situ: Protocol Evaluating the Assessment of Extension of Disease by MRI

Status Completed

Clinical Trial Summary

RATIONALE: Diagnostic procedures, such as MRI, may help find ductal carcinoma in situ and find out how far the disease has spread.

PURPOSE: This clinical trial is studying how well MRI works in assessing tumor size in women with ductal carcinoma in situ.

Clinical Trial Description

OBJECTIVES:

Primary

• Assess the contribution of MRI in accurately determining tumor size in women with ductal breast carcinoma in situ (DCIS).

Secondary

• Evaluate the sensitivity of MRI in detecting DCIS.

• Evaluate the contribution of mammography in accurately determining tumor size.

• Compare the contribution of MRI vs mammography in assessing tumor extension.

• Compare the contribution of MRI vs mammography in assessing dense breasts.

• Evaluate the morphology of DCIS by MRI.

• Evaluate the curve of dynamic MRI in assessing DCIS.

• Evaluate the impact of nuclear grade of DCIS by MRI.

• Evaluate the rate of revision surgery.

OUTLINE: Patients undergo clinical examination, mammography, ultrasound imaging, unilateral breast MRI, and tissue sampling. ;

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Breast Cancer
• Carcinoma in Situ
• Carcinoma, Ductal
• Carcinoma, Intraductal, Noninfiltrating

• NCT number: NCT00874458
• Study type: Interventional
• Source: Centre Antoine Lacassagne
• Status: Completed
• Phase: N/A
• Start date: April 2007
• Completion date: December 2013