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Brain Structure clinical trials

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NCT ID: NCT05912556 Recruiting - Cognition Clinical Trials

Brain Response to an Intervention Using Guided, At-Home Technology for the Mind

BRIGHT-Mind
Start date: July 5, 2023
Phase: N/A
Study type: Interventional

The objective of this study is to assess the effectiveness of two digital programs for providing mental stimulation, improving cognition, and inducing changes in brain structure and function.

NCT ID: NCT05277558 Recruiting - Inflammation Clinical Trials

Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)

Metabrain
Start date: May 24, 2022
Phase:
Study type: Observational

Investigators propose to study youth across the spectrum of body mass index (BMI) and dysglycemia. This approach will allow investigators to disentangle the relationship of key features of type 2 diabetes (T2D) risk (e.g. obesity) with intermediary physiologic changes (e.g. insulin resistance, inflammation, β-cell dysfunction and dysglycemia) that pose a risk for the brain. Investigators will determine which of these factors are most associated with differences in brain structure and function among groups, over time, and how these effects differ from normal neurodevelopment.

NCT ID: NCT04856410 Enrolling by invitation - Clinical trials for Cognitive Performance

Effects of Long-Duration Spaceflight on General and Spatial Cognition and Its Neural Basis

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

This study investigates the effects of extended-duration spaceflight (12-month International Space Station missions) on general cognitive performance (measured with the Cognition test battery), spatial cognition, structural and functional brain changes in general, and hippocampal plasticity more specifically relative to the shorter 6-month and 2-month missions.

NCT ID: NCT03771716 Active, not recruiting - Clinical trials for Cognitive Performance

Rhythm Experience and Africana Culture Trial

REACT
Start date: May 21, 2019
Phase: N/A
Study type: Interventional

REACT is a randomized intervention to examine the benefits of African Dance as a method to increase physical activity behaviors in older adults. In this 6- month intervention, older African Americans will be randomly assigned to either an African Dance or an Africana Culture class. Both before and at the completion of the intervention, the investigators will collect a comprehensive neuropsychological battery and MRI scans of brain health and function to better study how physical activity influences neurocognitive health in African Americans.