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Effect of Bevacizumab on Asymptomatic Radiotherapy-induced Brain Injury — BRAIN  

Brain Injuries Clinical Trial

Official title:
Effect of Bevacizumab on Asymptomatic Radiotherapy-induced Brain Injury in Patients With Head and Neck Cancer

Clinical Trial Summary

To investigate the effect of Bevacizumab on asymptomatic radiotherapy-induced brain injury patients with head and neck cancer.

Clinical Trial Description

Radiotherapy-induced brain injury (RI) is a serious complication of radiotherapy in head and neck cancer (HNC) patients. Previous studies have confirmed that Bevacizumab has a good effect on patients with symptomatic RI .However, patients with RI maybe do not show clinical symptoms in the early stage. The clinical symptoms will appear with the progression of the RI lesion. There has been no relevant research on whether early intervention is necessary for asymptomatic RI. The investigators conduct this multicenter, randomized clinical research to explore the efficacy and safety of Bevacizumab in asymptomatic RI. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05303259
Study type Interventional
Source Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Contact Yamei Tang, PHD
Phone +86 13556001992
Email tangym@mail.sysu.edu.cn
Status Recruiting
Phase Phase 2
Start date November 1, 2021
Completion date December 30, 2025
View Details
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