Intermittent Hypoxia Paired With High Intensity Training in Brain Injury

Brain Injuries Clinical Trial

Official title: Intermittent Hypoxia Paired With High Intensity Training in Brain Injury

Status Completed

Clinical Trial Summary

The central hypotheses are that HIT combined with AIH results in: 1) greater locomotor gains as compared to HIT alone; 2) improvements in gait quality and motor coordination during walking, and 3) changes in measures of community participation and integration.

Clinical Trial Description

The central hypotheses are that HIT combined with AIH results in: 1) greater locomotor gains as compared to HIT alone; 2) improvements in gait quality and motor coordination during walking, and 3) changes in measures of community participation and integration. To test these hypotheses, the proposed crossover, assessor-blinded, randomized clinical trial (RCT) is designed to test the effects of safety, feasibility, and preliminary efficacy of HIT+AIH. In this phase I-II trial, patients >6 months post-BI with mobility deficits will be allocated to 5 weeks (15 sessions) of HIT+AIH or HIT alone. Blinded assessments will be performed prior to and following training paradigms to address 3 specific aims. ;

Related Conditions & MeSH terms

• Brain Injuries
• Hypoxia
• Wounds and Injuries

• NCT number: NCT04472442
• Study type: Interventional
• Source: Indiana University
• Status: Completed
• Phase: N/A
• Start date: August 1, 2020
• Completion date: June 30, 2023