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Bowel Preparation clinical trials

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NCT ID: NCT02761317 Recruiting - Bowel Preparation Clinical Trials

Optimal Bowel Preparation Regimen in Patients With Colorectal Surgery

Start date: May 2016
Phase: Phase 4
Study type: Interventional

The study compares the efficacy of bowel cleansing between the standard preparation (2 L polyethylene glycol electrolyte solution, 2 L PEG-ELS), low-volume preparation (10 mg bisacodyl plus 2 L PEG-ELS) and high-volume preparation (4 L PEG-ELS) in patients with previous colorectal resection.

NCT ID: NCT02536729 Not yet recruiting - Bowel Preparation Clinical Trials

Evaluation of the Quality of Life of Patients Requiring Intestinal Cleansing Using Oral Medications to Imaging Procedure by Patient Reported Outcome

Start date: September 2015
Phase: N/A
Study type: Observational

Objective: The primary objective of this study is to assess the quality of life of people treated with oral phosphate compared with polyethylene glycol + electrolytes to imaging procedures, according to the outcome variables reported by patients. Type of study: A non-interventional observational analytic prospective cohort study. Sample: We will include people who need bowel cleansing for the realization of imaging tests Exposures: - oral sodium phosphate normal regimen - Oral sodium phosphate with modified diet - Polyethylene Glycol + electrolytes Follow-up time: 8 days after the bowel preparation Outcomes: Boston Scale measure Safety Differences between groups in blood test (Sodium, Potassium, Calcium)

NCT ID: NCT02402270 Completed - Bowel Preparation Clinical Trials

Safety and Tolerability Study of an Edible Colon Preparation

Start date: May 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to learn about a new bowel preparation that uses food to clean the colon. In order to learn about this new food preparation, some people in this study will get the food preparation, and others will get the standard liquid bowel preparation. Patients will be randomized (like flipping a coin) to one of five groups: Group 1 - Menu A Meal Kit - contains bars, shakes, soup, and a rice bowl Group 2 - Menu B Meal Kit - contains bars, shakes, soup, and a rice bowl Group 3 - Menu C Meal Kit - contains bars and shakes Group 4 - MoviPrep Group 5 - NuLYTELY

NCT ID: NCT02396017 Recruiting - Bowel Preparation Clinical Trials

Split-dose Versus Single-dose Polyethylene Glycol Regimen for Capsule Endoscopy

Start date: March 2015
Phase: Phase 4
Study type: Interventional

To compare the small bowel cleanliness for wireless capsule endoscopy using two different Polyethylene Glycol administration schedules (before the wireless capsule endoscopy ingestion versus in a split-dose fashion).

NCT ID: NCT02386449 Completed - Bowel Preparation Clinical Trials

A Study Comparing Picoprep With Mannitol and Bisacodyl for Colon Cleansing in Preparation for Colonoscopy

CLEAR PREP
Start date: February 2015
Phase: Phase 4
Study type: Interventional

This is a randomized, controlled, parallel group, assessor-blinded study to compare two colon cleansing preparations for colonoscopy. Subjects meeting all inclusion and exclusion criteria will be randomized and assigned to one of two study groups: Group I (PicoPrep) or Group II (Mannitol). In Group I, subjects will take one sachet of PicoPrep on the day before colonoscopy, and another sachet on the day of colonoscopy. In Group II, subjects will take Bisacodyl on the day before colonoscopy, and Mannitol on the day of colonoscopy.

NCT ID: NCT02290093 Completed - Colonoscopy Clinical Trials

Bowel Preparation for Colonoscopy in the Elderly

Start date: November 2014
Phase: Phase 4
Study type: Interventional

The success of colonoscopy is closely related to the quality of colonic preparation. However, data regarding colonoscopy preparations in the elderly (65 years older) are scarce. Split-dosage cathartic bowel preparation are currently suggested, whereas supporting evidence is lacking in this particular group of patients. Moreover, patient tolerability is a key factor for success of bowel preparation in the aged people. The purpose of this study is to compare the bowel cleansing efficacy and patient compliance of following bowel preparation methods prior to elective outpatient colonoscopy in the elderly: (1) standard preparation of 4 liters (L) PEG-3350 solution on the night before colonoscopy, (2) split-dose of 4L PEG-3350 solution, and (3) split-dose of reduced volume [2L] PEG-3350 containing ascorbic acid solution.

NCT ID: NCT02174497 Completed - Bowel Preparation Clinical Trials

One-Day Versus Three-Day Bowel Preparation for Colonoscopy in Children

Start date: February 2008
Phase: N/A
Study type: Observational

This was a blinded study conducted on the efficacy and safety of a one-day versus a three-day bowel preparation in a pediatric population. Limited data is available in this regard, and this study supports the use of a one-day bowel preparation, as this is both safe and effective.

NCT ID: NCT02140827 Completed - Bowel Preparation Clinical Trials

Instant Messaging Program (Wechat) Improve the Quality of Bowel Preparation

Start date: May 2014
Phase: N/A
Study type: Interventional

Colonoscopy is the gold standard in the diagnosis of colorectal disease. The success of colonoscopy depends on high-quality bowel preparation by patients. Inadequate bowel cleansing reduces the cecal intubation rate, and the polyp detection rate (PDR). It also increases costs, mostly due to repeated procedures. The quality of bowel cleansing has remained suboptimal even though numerous different products and regimens have been tested and compared in no fewer than six meta-analyses. Therefore, a completely different approach to improve bowel cleansing is welcome. Here the investigators assume that instant messaging program (Wechat) delivery the detail and FAQ (Frequently Asked Questions) of bowel preparation instructions would improve the quality of the bowel preparation. The Wechat program has some advantages, 1. Wechat supports over 400 million users, nearly half of the mobile subscribers population in China; 2. Wechat provided a real time communications including voice messages, pictures and text exchange timely; 3.Compare with telephone, Wechat is economical of both time and money; 4. Compare with bowel preparation instructional software and litera or cartoon educational booklet, Wechat is more interactive and responsive.

NCT ID: NCT02093156 Completed - Bowel Preparation Clinical Trials

A Predictive Score Identifies Patients With Inadequate Bowel Preparation for Colonoscopy

Start date: September 2013
Phase: N/A
Study type: Observational [Patient Registry]

Colonoscopy is the current standard method for evaluating the colorectal diseases. Adequate bowel preparation is essential for optimal visualization of the colorectal mucosa. However, inadequate bowel preparation (IBP) had been unexpectedly reported in up to 30% of patients undergoing colonoscopy. Many factors may influence the quality of bowel preparation, which can be broadly categorized as patient-related or procedure-related. It has been shown that split-dose regimen or some modified educational strategies can improve the quality of bowel preparation. For the patients with possible IBP before the performing of colonoscopy, it may be better to repeat bowel preparation with modified or enhanced strategies in case of failed intubation, missed lesions or unnecessarily increased cost. Thus, it is important to set up a model to predict the quality of bowel preparation individually.

NCT ID: NCT02070341 Terminated - Bowel Preparation Clinical Trials

Patient Tolerability and Efficacy of Bowel Preparation With Split Dose Picosalax vs. Split Dose PEG

Start date: February 2014
Phase: Phase 4
Study type: Interventional

Introduction: Colonoscopy is an important tool for colon cancer screening. Proper colon cleansing is essential to ensure adequate mucosal examination. Timing of bowel preparation administration is now recognized as an important component for achieving superior cleansing. Multiple randomized controlled trials and meta-analyses have found split-dosing to be superior than day-before dosing. Objective: This study aims to compare two types of bowel preparations in split-doses to assess for differences in patient tolerability, as well as efficacy of colon cleansing. Methods: This is a prospective, single-blinded, randomized-controlled trial. Patients who are being referred for a colonoscopy will be recruited to participate in the study. They will be randomly assigned to receive either a split-dose polyethylene glycol (PEG) or picosalax (P/MC) bowel preparation. Patient tolerability will be examined through questionnaires. The endoscopist performing the colonoscopy will use two standardized bowel preparation scoring systems to evaluate the quality of the cleansing. The investigators propose that P/MC will be superior to PEG in patient tolerability and non-inferior in bowel cleansing effects.