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Bowel Preparation clinical trials

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NCT ID: NCT05870553 Completed - Bowel Preparation Clinical Trials

A Phase 3 Trial in Bowel Preparation for Colonoscopy

Start date: January 30, 2023
Phase: Phase 3
Study type: Interventional

This is a prospective randomized study compared with active control arm. The investigators compare the colon cleansing in patients undergoing colonoscopy.

NCT ID: NCT05801250 Not yet recruiting - Bowel Preparation Clinical Trials

A Deep Learning-based System for the Bowel Preparation Evaluation Before Colonoscopy

Start date: April 2, 2023
Phase: N/A
Study type: Interventional

Educational interventions provided to patients may improve colon cleansing. The aims of this study were to develop an AI platform which can help patients evaluate the adequacy of bowel cleansing without the aid of caregivers and to investigate whether there was a statistically positive correlation between the Image rating and the BBPS score.

NCT ID: NCT05726344 Completed - Colonoscopy Clinical Trials

Lactulose vs. Polyethylene Glycol as Bowel Preparation for Colonoscopy in Adults

Start date: February 10, 2023
Phase: N/A
Study type: Interventional

Colonoscopy is the gold standard in bowel assessment when there is suspicion of colon and rectum pathology. Bowel cleansing is necessary to ensure an optimal visualization of colonic mucosa, allowing this form of detection and removal of polyps. Nowadays international recommendations have multiple bowel preparations. There are differences among them regarding adherence, tolerance and adverse effects. Lactulose (LAC) is widely used in treating constipation. However, there are some randomized clinical assays using LAC as bowel preparation with excellent results according to bowel preparation and tolerance scales. Adherence to bowel preparation significantly affects the result in the endoscopic study. Safety of polyethylene glycol (PEG) formulations has been validated in several studies, it presents little severe side effects and the advantage of its applicability to patients with several comorbidities (heart, liver and kidney without water deprivation). However, its main disadvantage lies in the need to ingest large amounts of liquid (3-4L), generating intolerance thereto in 15%-45% of patients. Bowel cleansing preparation with PEG is widely used in clinical practice. Considering that according to international studies reporting better tolerance and adherence with LAC; it is suggested to compare the level of bowel preparation, tolerance and adherence between two groups with LAC and PEG.

NCT ID: NCT05670470 Completed - Bowel Preparation Clinical Trials

A Prospective, Randomized, Investigator-blinded, Parallel, Multi-center, Phase 3 Trial

PROPELLER
Start date: September 21, 2022
Phase: Phase 3
Study type: Interventional

This is a prospective randomized study compared with active control arm.

NCT ID: NCT05609591 Recruiting - Bowel Preparation Clinical Trials

Three Dietary Regimens in Pre-colonoscopic Bowel Preparation in Children

Start date: November 9, 2022
Phase: N/A
Study type: Interventional

To describe the feasibility and effectiveness of three dietary regimens in precolonoscopy bowel preparation in children

NCT ID: NCT05542810 Not yet recruiting - Bowel Preparation Clinical Trials

Compare the Effectiveness of Sports Drink and Water as a Solvent in Polyethylene Glycol for Colonoscopy

Start date: January 1, 2023
Phase: Early Phase 1
Study type: Interventional

In this study, 200 patients were enrolled from 2023.1.1 to 2023.12.31, and were randomly divided into intervention and control groups. The intervention group compared the effectiveness of intestinal preparation in the two groups with sports drinks as a polyethylene glycol solvent and water as a polyethylene glycol solvent in the intervention group, and compared adverse reactions, acceptability of solution taste, time of oral laxatives, willingness to repeat the same intestinal preparation or the willingness to recommend the same intestinal preparation to others.

NCT ID: NCT05137145 Recruiting - Bowel Preparation Clinical Trials

Effect and Safety of Polyethylene Glycol Combined With Linaclotide on Colon Cleansing for Patients With Chronic Constipation

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Constipation is a common reason of poor bowel preparation, which negatively influences the quality of colonoscopy. Clinically to explore more effective and tolerant bowel clearance programs is necessary for patients with chronic constipation.

NCT ID: NCT05107505 Recruiting - Bowel Preparation Clinical Trials

Evaluation of The Factors Affecting Bowel Preparation Adequacy for Colonoscopy

Start date: July 15, 2021
Phase:
Study type: Observational

A prospective observational study in order to: 1. st: Identify epidemiological, clinical, and preparation-related factors that can predict improper preparation leading to better management of the patients with non adequate preparation. 2. nd: Evaluation of the effect of the time of preparation and endoscopy initiation time on the outcome of intestinal preparation for colonoscopy.

NCT ID: NCT05088408 Completed - Colonoscopy Clinical Trials

Comparative Study Between Colonoscopy Bowel Preparation With Clear Liquids, With and Without Two Servings of High Energy Nutritional Supplement

Start date: October 30, 2020
Phase: Phase 4
Study type: Interventional

The high energy nutritional supplement Resource® Energy is approved for human nutritional support in various clinical conditions, yet it has been used off-label to alleviate the effects of hunger during bowel preparation for colonoscopy. Its impact in mucosa visualization quality and hunger alleviation is unknown. The product is liquid and nutritious but it is not transparent, thus it is conceivable that it could alleviate the discomfort of hunger during the preparation but possibly compromising mucosa visualization. In this study, participants who will undergo a colonoscopy (requested for an explicit medical indication) will take two bottles of the nutritional supplement during the usual bowel preparation. The quality of mucosal visualization and the participants opinion regarding satiety and product tolerance during bowel preparation will then be analysed.

NCT ID: NCT05041283 Recruiting - Bowel Preparation Clinical Trials

Impact of Artificial Intelligence-based Patient Reinforcement on Quality of Colonoscopy

ARCHES
Start date: May 21, 2021
Phase: N/A
Study type: Interventional

In order to improve bowel preparation for colonoscopy and consequently enhance detection rate of malignant and premalignant findings, a prospective, randomized and controlled three-arm study was developed. Patients who undergo ambulatory colonoscopy are randomly assigned into a control group with standard preparation, a phone call supported preparation group or a group supported by an artificial intelligence based chatbot. Primary endpoint is defined as quality of bowel preparation (Boston Bowel Preparation Score), secondary endpoints are patients satisfaction, comprehensiveness of bowel preparation, sedation dose, rate of coecal intubation and the rate of adenoma and polyp detection, anxiety referred to colonoscopy and patients satisfaction with preparation support.