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Clinical Trial Summary

Constipation is a common reason of poor bowel preparation, which negatively influences the quality of colonoscopy. Clinically to explore more effective and tolerant bowel clearance programs is necessary for patients with chronic constipation.


Clinical Trial Description

Colonoscopy is an important method to screen, diagnose and treat colon lesions. The quality of bowel preparation is requisite for the accuracy of diagnosis and safety of treatment. To explore the application effect and safety of Linaclotide combined with Compound Polyethylene Glycol Electrolyte Powder on colon cleansing before colonoscopy in patients with chronic constipation. A prospective mult-centers, colonoscopist-blinded study was conducted. A total of 300 patients with constipation who underwent colonoscopy in 8 hospitals from July to December 2021 were selected as study subjects and divided into the control group, observation group 1, observation group 2 and observation group 3 by random number table method, with 75 cases in each group. Intestinal cleanliness and the incidence of adverse reactions of patients in each group were compared. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05137145
Study type Interventional
Source Second Affiliated Hospital of Xi'an Jiaotong University
Contact fei dai, MD
Phone 13772151298
Email daifei68@hotmail.com
Status Recruiting
Phase N/A
Start date September 1, 2021
Completion date April 30, 2022

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