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Efficacy and Safety of Oral Sulfate Solution on Bowel Preparation for Colonoscopy

Bowel Preparation for Colonoscopy Clinical Trial

Official title:
Comparison of the Efficacy and Safety of Oral Sulfate Solution and 3-liter Polyethylene Glycol on Bowel Preparation Before Colonoscopy: a Multicenter Randomized Controlled Phase III Trial

Clinical Trial Summary

To evaluate whether oral sulfate solution used for colon cleaning in adults prior to colonoscopy was not inferior to 3-liter polyethylene glycol in the proportion of subjects with BBPS score (total colon) ≥6 after colonoscopy

Clinical Trial Description

Polyethylene glycol (PEG) is the most widely used laxative at present, but volume of oral PEG liquid is large and the taste of PEG is not good, so some patients could not take enough laxative to complete bowel preparation. Oral sulfate solution containing sodium sulfate, magnesium sulfate, and potassium sulfate as active ingredients was developed as osmotic laxative for bowel cleansing preparation. The OSS works on the principle that sulfate is a poorly absorbed anion. Compared to traditional magnesium sulfate solution, OSS not only tastes better, but also reduces the occurrence of electrolyte disturbances. ;

Study Design

Related Conditions & MeSH terms

  • Bowel Preparation for Colonoscopy
Clinical Trial Details
NCT number NCT05465889
Study type Interventional
Source Changhai Hospital
Contact
Status Completed
Phase Phase 3
Start date May 15, 2019
Completion date March 15, 2020
View Details
See also
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