Bowel Preparation for Colonoscopy Clinical Trial
Official title:
Efficacy and Tolerability of Low-volume Polyethylene Glycol (2 L) vs. Single- (4 L) vs. Split-dose (2L + 2L) of Polyethylene Glycol Bowel Preparation for Colonoscopy: a Randomized Clinical Trial.
the efficacy and tolerability of a low-volume (2 L) PEG regimen for colonoscopy compared to single (4 L) or split-dose (2 L + 2 L) treatments are not different.
In-hospital patients were randomly assigned to one of three groups: group 1 single dose
(PEG-3350; PEG-4 L the day previous of the study, starting at 17:00 and finishing at 21:00
h); group 2: split-dose (PEG-3350; 2 L the day before 17:00-19:00 h and 2 L same day of the
procedure 06:00-08:00 am); group 3: low-volume 2 L PEG-solution (same day of the procedure
06:00-08:00 am).
The quality of colonic preparation was assessed by the Boston bowel preparation scale (13);
tolerability (nausea, vomiting, and abdominal pain), compliance, sleep disturbance and
adverse effects in group 3 were compared with those in groups 1 and 2. The time since the
last dose of bowel-preparation agent, the time since the last solid food was consumed, the
approximate amount of bowel preparation taken (0%, 25%, 75%, or 100%), and the start time of
the colonoscopy were recorded.
Satisfactory colon preparation was considered when scores of the Boston bowel preparation
scale were 2/3; otherwise, the procedure was considered unsatisfactory preparation.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Diagnostic
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02839824 -
Evaluation of the Quality of Bowel Cleansing in a Real Clinical Practice Setting
|
N/A | |
| Completed |
NCT01719653 -
A Comparison of 5 Low Volume Bowel Preparations
|
Phase 4 | |
| Completed |
NCT00611442 -
Split Dose Golytely With Amitiza Pretreatment Versus Split Dose Golytely Plus Placebo in Outpatient Colonoscopy
|
N/A | |
| Recruiting |
NCT01028573 -
A Study Comparing PEG-3350 (Miralax) and Gatorade With PEG-ELS (Golytely) for Bowel Preparation Prior to Colonoscopy
|
N/A | |
| Completed |
NCT05291325 -
Application of Linaclotide Capsule in Bowel Preparation for Colonoscopy
|
N/A | |
| Not yet recruiting |
NCT01853709 -
Multidisciplinary Approach Versus Conventional Approach in Colonic Preparation of Hospitalized Patients
|
Phase 4 | |
| Completed |
NCT01415687 -
Split Dose Pico-Salax + Bisacodyl vs. PEG Split Dose
|
Phase 3 | |
| Completed |
NCT05465889 -
Efficacy and Safety of Oral Sulfate Solution on Bowel Preparation for Colonoscopy
|
Phase 3 | |
| Completed |
NCT03055689 -
Bowel Preparation for Repeat Colonoscopy After Preparation Failure (RepeatPrep Study)
|
N/A | |
| Completed |
NCT02376465 -
A Pilot Evaluation of an Experimental BLI4600 Formulation for Bowel Preparation in Adult Patients Undergoing Colonoscopy
|
Phase 2 | |
| Completed |
NCT01765491 -
Comparison of Two Methods of Bowel Preparation for Colonoscopy in Hospitalized Patients
|
N/A |