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Trabectedin Plus Olaparib in Metastatic or Advanced Sarcomas (TOMAS) — TOMAS  

Soft Tissue Sarcoma Clinical Trial

Official title:
A Phase Ib Study on the Combination of Trabectedin and Olaparib in Unresectable Advanced/Metastatic Sarcomas After Failure of Standard Therapies

Clinical Trial Summary

This is a Phase 1b, multi-site, open-label, non-randomized clinical trial evaluating the safety, tolerability, and pharmacokinetics of escalating doses of olaparib and trabectedin in patients with unresectable advanced/metastatic sarcomas. Patients will continue to be treated on this combination regimen in the absence of disease progression, intolerable toxicity or patient's decision.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02398058
Study type Interventional
Source Italian Sarcoma Group
Contact
Status Completed
Phase Phase 1
Start date July 20, 2014
Completion date December 1, 2019
View Details
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