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Blood Pressure clinical trials

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NCT ID: NCT05349422 Active, not recruiting - Blood Pressure Clinical Trials

Addressing Antihypertensive Medication Adherence Through EHR-enabled Teamlets in Primary Care

Start date: October 6, 2022
Phase: N/A
Study type: Interventional

The study team will conduct a cluster randomized control trial in 10 NYU primary care practices to assess the effectiveness and implementation of the multicomponent intervention on medication adherence and blood pressure control for patients who are non-adherent to antihypertensive medications.

NCT ID: NCT05341921 Recruiting - Blood Pressure Clinical Trials

Deep Breathing Techniques (Pranayama) in Pregnancy

Start date: August 2, 2022
Phase: N/A
Study type: Interventional

Slow deep breathing actives the vagal nerve and leads to a natural reduction in physiological parameters such as blood pressure, heart rate and digestion. The effects of these techniques have not been assessed in pregnancy. The primary objective is to assess the effects of various yogic deep breathing techniques on blood pressure during pregnancy. The breathing exercises will include Alternate nostril breathing, Bhramari breathing, and Sheetali breathing. A secondary objective will be to assess the effects of these breathing exercises on other physiological parameters including heart rate, heart rate variability, body temperature, cardiac output, vascular resistance and respiratory rate.

NCT ID: NCT05337787 Completed - Blood Pressure Clinical Trials

Flipped Classroom Approach on Nursing Students' Blood Pressure

Start date: December 6, 2021
Phase: N/A
Study type: Interventional

Effects of the Flipped Learning Model on Blood Pressure Knowledge and Self-directed Learning Skills of First-Year Nursing Students: A Randomized Controlled Study

NCT ID: NCT05324306 Completed - Blood Pressure Clinical Trials

Tourniquets Increase Proximal Pressure

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

There is an urgent clinical need to improve survival and neurologic outcomes after cardiac arrest. When a patient goes into cardiac arrest, cardiopulmonary resuscitation (CPR) with chest compressions is the current standard of care treatment to mechanically circulate blood through the patient's body. The immediate and long-term success of CPR is critically dependent on the maintenance of adequate coronary and cerebral perfusion. The investigators propose that CPR outcomes can be improved by capitalizing on the innate mechanism of vasoconstriction and preferentially routing the limited oxygenated blood to the heart and brain. The proposed solution is occlusion of extremity vasculature will increase coronary and cerebral perfusion and improve patient outcomes after cardiac arrest. Prior research has investigated the efficacy of manipulating peripheral vascular resistance with tourniquets in animal studies with improved cardiac and cerebral perfusion and survival. To prove this is an adequate solution in humans, the investigators plan to use tourniquets on the legs to occlude the peripheral vasculature in healthy humans and measure more proximal blood pressure before and after tourniquet deployment. Proof of concept of this solution will make way for development of novel devices for use during cardiac arrest and CPR to improve heart and brain perfusion and ultimately improve cardiac arrest outcomes. The investigators will recruit 30 healthy human participants and measure their blood pressure in their arm. They will then place two commercially-available, FDA-approved tourniquets around each thigh to stop blood flow to the legs. The investigators will measure the blood pressure in the arms again. They will then release the tourniquets after blood pressure measurement. This will be repeated three times with breaks between each repetition.

NCT ID: NCT05310006 Completed - Blood Pressure Clinical Trials

Acute Effects of Low and High-Speed Resistance Training on Blood Pressure in Older Adults: A Crossover Study

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

The first study was a randomized crossover trial that compared the acute effects of High Speed Resistance Exercise (HSRE) and Traditional Resistance Exercise (TRE) on blood pressure parameters in a sample of frail older adults. Participants performed three experimental sessions (i.e., HSRE, TRE, and a control session [CS]) in a random order and separated from one another by seven days (standard deviation [±] 1 day). Food consumption was maintained constant during 48 h prior to the exercise session and a standard breakfast was offered 60-90 min before the beginning of the experimental sessions. The pharmacological therapy was kept constant during the whole study, and participants took their anti-hypertensive medication at the same time in all experimental days as prescribed by their physician.

NCT ID: NCT05305118 Recruiting - Blood Pressure Clinical Trials

TSCS for Acute SCI

Start date: March 18, 2022
Phase: N/A
Study type: Interventional

This project will focus on a novel approach to stabilizing blood pressure (BP) during inpatient rehabilitation after acute SCI. After SCI, people have unstable blood pressure, ranging from too low (orthostatic hypotension) to too high (autonomic dysreflexia). Unstable BP often interferes with performing effective physical rehabilitation after SCI. A critical need exists for the identification of safe, practical and effective treatment options that stabilize BP after traumatic SCI. Transcutaneous Spinal Cord Stimulation (TSCS) has several advantages over pharmacological approaches: (1) does not exacerbate polypharmacy, (2) can be activated/deactivated rapidly, and (3) can be applied in synergy with physical exercise. The study team is asking the key question: "What if applying TSCS earlier after injury could prevent the development of BP instability?" To facilitate adoption of TSCS for widespread clinical use, the study team plans to map and develop a parameter configuration that will result in an easy to follow algorithm to maximize individual benefits, while minimizing the burden on healthcare professionals. This project will provide the foundational evidence to support the feasible and safe application of TSCS in the newly injured population, thereby overcoming barriers to engagement in prescribed inpatient rehabilitation regimens that are imposed by BP instability.

NCT ID: NCT05302193 Recruiting - Blood Pressure Clinical Trials

Non-invasive Blood Pressure Measurement Using Samsung Smartwatch

Start date: February 15, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to verify the accuracy of blood pressure and heart rate measurement by Samsung smartwatches compared to a standard monitor of vital signs used in intensive care units.

NCT ID: NCT05299450 Completed - Blood Pressure Clinical Trials

Pre-conception Interventions to Reduce Blood Pressure Before Pregnancy

CONCEIVE 2
Start date: December 1, 2020
Phase: N/A
Study type: Interventional

The study proposes to evaluate the feasibility of a preconception intervention comprising two proven interventions for reducing blood pressure; Beetroot juice; a source of dietary nitrate which reduces BP by 8/4mmHg after 4 weeks(6); Personalised resistance and endurance exercise programme (as per CMO recommendations) which reduces BP by ~10/5mm Hg over 8-12 weeks (7).

NCT ID: NCT05291143 Completed - Hypertension Clinical Trials

The Effectiveness of Short Videos on HBPM

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

Hypertension prevalence among Malaysian adults is high at around 30% and is also reported to be the highest risk factor for mortality in Malaysia. Home Blood Pressure Monitoring (HBPM) has been proven to improve blood pressure levels for at least twelve months when used in conjuction with co-inventions such as education interventions or support from health care professionals. Social media has been described as having a favourable role in health interventions due to its popularity with vast numbers of users particularly the younger adults, its advantages mainly in health communication with patients, plus its promising impact on behavioural change. It has been reported that around 15% of those with hypertension are young adults; aged between 18-39 years. Therefore, this may be a good start to plan an intervention program on hypertension using the concept of short videos as popularised by social media; particularly on home blood pressure monitoring. As students are future doctors and can act as advocate in sharing important healthcare knowledge to family members and friends, they are the best candidate to be chosen as subjects of this research.

NCT ID: NCT05283824 Completed - Blood Pressure Clinical Trials

Comparison of 3 Techniques for Blood Pressure Measurements During Interventional Neuroradiology Procedures

NEXFIN-NRI
Start date: March 19, 2022
Phase:
Study type: Observational

Some observational studies demonstrated that hypotension was associated with post-operative morbidity. During neuroradiological procedures, cerebral perfusion pressure should be cautiously maintained and hypertension should also be avoided. So, a precise arterial pressure measurement is needed during this procedures. A continuous monitoring of arterial pressure needed the placement of an arterial catheter in radial artery. The placement of this catheter might be long, difficult and incompatible with emergency neuroradiological procedure (such as thrombectomy). Then, this invasive technique is associated with several minor and major side effects such as: pain, infection, thrombosis, hematoma. The Clearsight®, commercialized by Edwards Life Science Company®, is a non invasive device which mesure continuously arterial pressure with Volume-Clamp method. In operating room, some studies found a good accuracy between Clearsight® and other invasive monitoring system. There is no description of the use of Clearsight® during neuroradiological procedures. The investigators hypothesized that Clearsight® measurement of arterial pressure are concordant with arterial pressure measure with the placement of an arterial catheter. The investigators also plan to evaluate accuracy of intermittent non invasive pressure measurement with traditional cuff.