Blood Coagulation Disorders, Inherited Clinical Trial
Official title:
Evaluation of Hemostasis in Bleeding and Thrombotic Disorders Using the Roteg Analyzer and the Thrombin Generation Assay
The objective of this study will be to assess the coagulation system in-vitro in a variety of bleeding and clotting disorders using the ROTEG analyzer and the thrombin generation assay.
This is an exploratory study involving blood coagulation assays in a select group of individuals. The ROTEG is a newly developed coagulation analyzer which allows the continuous assessment of whole blood coagulation from the formation of the first fibrin fibers and activated platelets, to the formation of a three-dimensional whole blood clot until the eventual dissolution of the clot. This device will not be used as a diagnostic or procedure tool. No recommendations regarding interpretation of the results or implications for future treatment will be provided. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT01339611 -
Education Program for Patients Receiving Oral Anticoagulation
|
N/A | |
| Completed |
NCT03734588 -
Dose-finding Study of SPK-8016 Gene Therapy in Patients With Hemophilia A to Support Evaluation in Individuals With FVIII Inhibitors
|
Phase 1/Phase 2 | |
| Completed |
NCT03876301 -
Lead-in Study to Collect Prospective Efficacy and Safety Data of Current FVIII Prophylaxis Replacement Therapy in Adult Hemophilia A Participants
|
||
| Completed |
NCT04272554 -
AAV Gene Therapy Screening/Observational Protocol (ECLIPSE)
|