Effects of Electroconvulsive Therapy (ECT) in Bipolar Depression

Status Withdrawn

Clinical Trial Summary

The primary purpose of this study is to use magnetic resonance spectroscopy (MRS) to measure the levels of several brain chemicals including, but not limited to, glutamate, glutamine, and N-acetylaspartate, before and after treatment with ECT. In addition to MRS, the investigators will use several other MRI techniques including structural MRI, resting state functional MRI (fMRI), and diffusion tensor imaging (DTI) to measure how the structure and function of the brain changes with ECT.

The investigators hypothesize that the Gln/Glu ratio is increased in the anterior cingulate cortex (ACC), but not the parieto-occipital cortex (POC), following the first ECT treatment.

Clinical Trial Description

n/a

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Bipolar Disorder

Clinical Trial Details

NCT number	NCT01557933
Study type	Observational
Source	Mclean Hospital
Contact
Status	Withdrawn
Phase	N/A
Start date	April 2011
Completion date	July 2012

View Details

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