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Clinical Trial Summary

This study is a 4-month open-label study of lithium in the acute treatment of patients with bipolar I or II disorder. Eligible patients will receive lithium 300 mg twice daily and titrated in 300 mg increments every 7 days as tolerated to levels > 0.6 mEq/L. Blood samples are collected at baseline and at the end of study. Analyses of 45 molecule expressions in mononuclear blood cells at baseline and endpoint will be carried out after the completion of study. Fifty patients meeting Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) criteria for bipolar I or II will be enrolled.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02909504
Study type Interventional
Source University Hospitals Cleveland Medical Center
Contact
Status Terminated
Phase Phase 4
Start date September 2016
Completion date November 2018

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