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Neural Correlates for Therapeutic Mechanisms of Lithium in Bipolar Disorder

Bipolar Disorder Clinical Trial

Official title:
A Multimodal Brain Imaging Study to Investigate Neural Correlates for Therapeutic Mechanisms of Lithium in Bipolar Disorder: Glycogen Synthase Kinase 3β Single Nucleotide Polymorphisms and Gray Matter Volume Increase Following Lithium Treatment in Bipolar Disorder

Clinical Trial Summary

The investigators will assess Li-induced gray matter volume changes with regard to the endophenotype of GSK3beta polymorphism. The changes of gray matter are supposed to be more attributable to neurotrophic and neuroprotective characteristics of Li, which were closely related to the inhibition of apoptotic activity of GSK3beta.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01543724
Study type Interventional
Source Ewha Womans University
Contact
Status Withdrawn
Phase Phase 4
Start date June 1, 2015
Completion date December 31, 2017
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