Bipolar Disorder Clinical Trial
Official title:
The Effects of Cognitive Remediation on Cognitive Function in Remitted Bipolar Disorder - a Proof of Concept Study (REMEDI)
Cognitive remediation (CR) is a new psychological treatment, which aims to improve cognitive
function and coping skills. Several studies have recently demonstrated that CR improves
cognitive and occupational function in patients with schizophrenia and with depression (e.g.
Wykes et al 2007, Elgamal et al 2007). However, it is unclear whether CR improves cognitive
and socio-occupational function in individuals with bipolar disorder (BD) and, if so, what
impact this might have on these people's abilities in terms of work, coping strategies,
quality of life, and everyday safety.
The aim of the present PhD study is to investigate if CR has beneficial effects on cognitive
and socio-occupational function in patients with previous mania and depression who
experience persistent cognitive difficulties. Such effects would suggest implementation of
CR in future treatment of bipolar disorder in order to facilitate the patients' ability to
cope with the responsibilities related to work and everyday life. The hypotheses of the
present study are that CR (in comparison to standard treatment) will 1) improve verbal
learning and recall; and 2) improve sustained attention, executive function and psychosocial
function.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
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