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Neuroimaging Studies of the Treatment of Bipolar Depression With Citalopram

Bipolar Depression Clinical Trial

Official title:
Neuroimaging Studies of the Treatment of Bipolar Depression With Citalopram

Clinical Trial Summary

Regional metabolic changes associated with response to 6 weeks of citalopram treatment, using 18-Fluorodeoxyglucose Positron Emission Tomography imaging, will be characterized (FDG PET).

Clinical Trial Description

Regional metabolic changes associated with response to 6 weeks of citalopram treatment, using 18-Fluorodeoxyglucose Positron Emission Tomography imaging, will be characterized (FDG PET). The following hypothesis will be tested: Antidepressant response or remission in depressed BPD patients will be associated with changes in cortical (prefrontal, parietal, premotor) and paralimbic (hippocampus, anterior cingulate, subgenual cingulate, posterior cingulate, and anterior insula) regions, consistent with SRI antidepressant response in unipolar depressed patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01639482
Study type Observational
Source Massachusetts General Hospital
Contact
Status Completed
Phase
Start date April 2010
Completion date December 2013
View Details
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