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Bipolar clinical trials

View clinical trials related to Bipolar.

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NCT ID: NCT02189057 Completed - Depression Clinical Trials

A Pharmacokinetic/Pharmacodynamic Genetic Variation Treatment Algorithm Versus Treatment As Usual for Management Of Depression

MOD
Start date: November 2014
Phase: N/A
Study type: Interventional

The overall goal of this investigator-initiated trial is to evaluate the treatment outcome of depression utilizing platform algorithm products that can allow rapid identification of pharmacokinetic (PK) and/or pharmacodynamic (PD) genomic variation. This new technology may have the potential to optimize treatment selection by improving response, minimizing unfavorable adverse events / side effects and increasing treatment adherence.

NCT ID: NCT02184767 Completed - BiPolar Clinical Trials

Study to Assess the Safety and Pharmacokinetics of ADASUVE® at Doses of 2.5, 5, or 10 mg in Children and Adolescents (10 Through 17 Years of Age) With Any Condition Warranting Chronic Use of an Antipsychotic Medication

Start date: July 2014
Phase: Phase 1
Study type: Interventional

This study is to assess the pharmacokinetics of loxapine and will be using plasma concentration data obtained over 48 hours after administration of the study drug

NCT ID: NCT02133170 Not yet recruiting - Depressive Symptoms Clinical Trials

"Mindfulness vs Psychoeducation in Bipolar Disorder"

BI-MIND
Start date: September 2014
Phase: N/A
Study type: Interventional

This is a parallel 3-group, multicenter, prospective, randomized, single-blind (evaluator) controlled pilot trial, with a 38- week follow-up. Patients diagnosed with bipolar disorder (BD) according to DSM -5 criteria for mild depression or subsyndromal depressive symptoms are assigned to one of the following 3 treatment groups: 1) psychopharmacological treatment plus Mindfulness Based Cognitive Therapy (MBCT); 2) psychopharmacological treatment plus structured group psychoeducation; 3) treatment as usual (TAU), including standard psychiatric care with standard pharmacologic treatment.

NCT ID: NCT01131559 Terminated - Depression Clinical Trials

Adjunctive Lisdexamfetamine (LDX) in Bipolar Depression

Start date: January 2010
Phase: Phase 3
Study type: Interventional

The specific aim of this study is to evaluate the efficacy and tolerability of lisdexamfetamine in the adjunctive treatment of bipolar disorder.

NCT ID: NCT01047215 Recruiting - Schizophrenia Clinical Trials

Heart Rate Changes in Schizophrenic and Bipolar Patients Under the Medication of Aripiprazole and Quetiapine

HeartAriQue
Start date: August 2009
Phase: Phase 4
Study type: Interventional

The goal of this research is investigating the heart rate changes in schizophrenic and bipolar patients under the medication of aripiprazole and quetiapine. In the mean time, we are hoping further investigating the interrelationship of medicine dosage and heart rate change, in order to acquire the best relationship both effectiveness as well as safety in acceptable heart rate change of clinical suggestion.

NCT ID: NCT00969930 Enrolling by invitation - Bipolar Clinical Trials

Genetic Association Study Between Single Nucleotide Polymorphisms (SNPs) and Cognitive Performance in Young Bipolar Type I Patients: LICAVALGENE

Licavalgene
Start date: August 2009
Phase: N/A
Study type: Observational

This is a genetic association study of cognitive impairment in young bipolar disease type I patients without medications in mania, depression, hypomania or mixed states.

NCT ID: NCT00666432 Completed - Schizophrenia Clinical Trials

Bipolar and Schizophrenia Consortium for Parsing Intermediate Phenotypes

Start date: May 2008
Phase:
Study type: Observational

Briefly, this multisite study is designed to identify endophenotypes (i.e., heritable biomarkers) associated with either schizophrenia or bipolar disorder alone, or both together. The subsequent genetic analyses will search genomic loci and candidate genes associated with each of the independent endophenotypes. This is a five site study that is slotted for NIMH funding.

NCT ID: NCT00300820 Completed - Bipolar Clinical Trials

Perspectives of Individuals With Bipolar Disorder and Siblings of Individuals With Bipolar Disorder; A Telephone Interview Study

Start date: March 2, 2006
Phase: N/A
Study type: Observational

This study will examine those who will seek and those who are most likely to benefit from genetic counseling for psychiatric disorders. It will identify themes related to perceived risks, benefits, and possible motivations for seeking genetic counseling among families affected by bipolar disorder. It will then use those themes to generate a starting point for a framework to guide further research and to improve genetics services as they are currently practiced. Adults with bipolar disorder and the adult siblings of people with bipolar disorder are eligible for this study. In a 60- to 90-minute telephone interview, participants are asked questions related to their thoughts about the causes of bipolar disorder, their experiences with the illness, their concerns about the disorder occurring again in their families, and their feelings about the value of discussing these issues with health care professionals. They also are asked questions about the mental health of their close family members and their own mental health.