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Bereavement clinical trials

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NCT ID: NCT06302283 Enrolling by invitation - Bereavement Clinical Trials

Collateral Effects of Pandemics - Care for Informal Caregivers

COLLPAN-3A
Start date: March 2024
Phase:
Study type: Observational

The study is a workpackage in the German research consortium COLLPAN. The study will map collateral effects in terms of psychosocial and spiritual burden of informal caregivers during after the pandemic and identification/mapping of risk factors.It will also map available therapeutic and preventive interventions and relief of this burden for the present situation and for future pandemics.

NCT ID: NCT06246708 Recruiting - Bereavement Clinical Trials

Cultural Adaptation of a Self-help App for Grieving Syrian Refugees in Switzerland

Start date: January 29, 2024
Phase: N/A
Study type: Interventional

The goal of this pilot RCT is to investigate the acceptability and feasibility of an unguided culturally adapted self-help app for grieving Syrian refugees in Switzerland. Furthermore, the study will examine whether using the app has an effect on secondary outcomes (e.g., grief symptoms).The main questions it aims to answer are: - Is the self-help app culturally acceptable and feasible in this target group and what do we need to adapt? - Does the use of the self-help app reduce grief symptoms? (amongst other secondary outcomes) Participants will be asked to: - Complete a baseline assessment - then use the self-help app for 5 weeks - Complete a second assessment and participate in a short semi-structured interview regarding acceptability and feasibility. Researchers will compare an intervention group to a wait-list control group to see if the use of the self-help app has an effect on secondary outcomes.

NCT ID: NCT06191484 Recruiting - Suicide Clinical Trials

Risk and Resilience to Suicide Following Late-Life Spousal Bereavement

RISE
Start date: November 20, 2023
Phase: N/A
Study type: Interventional

The purpose of the RISE study is to examine how the 24-hour rhythm of sleep and social activity relate to mood and suicidal ideation among older adults that recently lost a spouse or life partner.

NCT ID: NCT06187636 Recruiting - Bereavement Clinical Trials

Parents Reflecting On Hope During Hospice Through Photovoice

Start date: January 30, 2024
Phase:
Study type: Observational

In this study, researchers will use Photovoice to learn about how bereaved parents felt and thought about hope when their children were on hospice. 'Photovoice' is a research method that uses participants' photographs as a springboard for discussion. Primary Objective - To explore reflections, emotions, and experiences evoked in bereaved parents when reviewing photographs from their child's time on hospice, with photos selected by parents based on a prompt related to their thoughts about hope during that time.

NCT ID: NCT06150859 Enrolling by invitation - Bereavement Clinical Trials

Ayahuasca Assisted Psychotherapy for Grief

PSICODUELAYA
Start date: October 15, 2021
Phase: Phase 2
Study type: Interventional

The aim of this study is to compare the effectiveness of an ayahuasca-assisted constructivist therapy with constructivist therapy and no treatment to decrease the severity of grief. A secondary purpose is to assess the effectiveness to prevent Persistent Complex Bereavement Disorder and Prolonged Grief Disorder, and to assess potential changes in avoidance, meaning-making and self-clarity. Subjective effects and Acceptance promoting effects of psychedelic drug are assessed after ayahuasca administration. A non-randomized controlled trial is proposed with three arms involving an experimental group (ayahuasca in concert with psychotherapy) and two control groups (psychotherapy and no treatment) with pretest, posttest and 3 months follow-up.

NCT ID: NCT06136260 Recruiting - Bereavement Clinical Trials

The Missing Pieces Trial: A Comparison of Two Interventions to Support Parents After Their Child's Unexpected or Traumatic Death

Start date: March 4, 2024
Phase: N/A
Study type: Interventional

Parents of children who die traumatically or unexpectedly from things like suicide or an overdose suffer from mental and physical health problems and can experience massive disruptions in their family life. For about half of these parents, the first, and sometimes only, interactions they have with the healthcare system when their child dies are with a medical examiner or coroner (hereafter 'ME'). But MEs have little to no training in helping grieving families, and there are no standards guiding medical examiners or coroners on how or even if they should help grieving families. This gap leaves parents to find the help they need on their own. This research will test two different strategies for addressing this gap in the healthcare system.

NCT ID: NCT06047808 Recruiting - Pediatric Cancer Clinical Trials

Feasibility Study of the Storytelling Through Music Intervention With Bereaved Parents

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

The death of a child, at any age, is considered one of the most stressful life events a person can experience. In 2020, 11,050 children (under 15 years), 5,000 adolescents (15-19 years) and 60,000 young adults (20-39 years) were estimated to be diagnosed with cancer in the US. While the five-year survival is better for children than adults, over 10,000 children, adolescents, and young adults die from cancer in the US each year.1 Bereaved parents often experience intense and lasting psychological distress resulting in significantly higher morbidity and mortality compared to non-bereaved parents. Twenty-five percent of bereaved parents report new diagnoses of illnesses including prediabetes, anxiety and sleep disorders. Bereaved parents also experience psychological distress such as anxiety, post-traumatic stress disorder, and grief-related depressive symptoms that continue to be significant for years after a child's death. A recent study showed that nearly 33% of bereaved parents suffered from prolonged grief five years after their loss.6 Physiologically, studies show increased cortisol, immune, endocrine, and cardio biomarkers in people with prolonged grief. The death of a child can also affect family and social relationships resulting in decreased communication, feelings of isolation, absence of close social relationships and increased marital strain and divorce. The purpose of this randomized controlled pilot study is to evaluate the feasibility of implementing a six-week multi-dimensional intervention, Storytelling Through Music (STM), with parents of children who have died from cancer. STM combines multiple modalities of expression (storytelling, writing, and music) to facilitate loss- and restoration-oriented coping by creating a legacy piece (self-written story paired with song) to facilitate continuing bonds with the deceased and find meaning.

NCT ID: NCT05867706 Not yet recruiting - Cancer Clinical Trials

Caregiver Burden and Bereavement-related Distress

Start date: September 2023
Phase:
Study type: Observational

The death of a spouse is considered one of the most stressful and impactful life events and is associated with increased morbidity and premature mortality. Early identification of individuals who are most at risk for poor health outcomes following bereavement is an important aim of precision medicine and disease prevention initiatives. A better understanding of caregiver burden and bereavement-related distress and its implication for health is a clinically-relevant step toward the development of treatments that improve health outcomes in bereaved spouses. This study aims to map profiles of individual differences in short- and long-term adjustment to loss, according to psychological (e.g., depression, stress, grief severity) and biological markers (e.g., inflammation, cortisol) over time.

NCT ID: NCT05826145 Not yet recruiting - Bereavement Clinical Trials

Bereavement Support Program for Caregivers

Start date: April 2023
Phase: N/A
Study type: Interventional

To provide a palliative bereavement support program for caregivers to decrease the risk for developing complicated and persistent grief.

NCT ID: NCT05803499 Recruiting - Quality of Life Clinical Trials

Rest to Overcome Loss and Reduce Risk

RESTore Plus
Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to develop and optimize a targeted behavioral intervention for sleep disturbance among individuals who have recently lost a spouse/long-term cohabitating partner. In the first phase of this study, patient focus groups were conducted to gather information about the unique sleep challenges experienced by spousally bereaved individuals and the kinds of support they would like to receive from a program based on Cognitive Behavior Therapy for Insomnia (CBT-I). In the second phase of the study, a two-arm randomized controlled trial will be conducted to compare changes in sleep and inflammation among participants in the targeted CBT-I intervention to those in an information-only control. Participants will be asked to attend two in-person visits (at baseline and, approx. 8 weeks later, at post-treatment) to provide a blood sample and have vital signs and basic anthropometric measurements (height, weight, waist circumference) taken. After their baseline visit, participants will be randomized into either the targeted CBT-I intervention or the information-only control. The targeted CBT-I intervention will entail 6 online sessions (approx. 50 mins. each) delivered via videoconference by a trained facilitator, once per week over the course of approx. 6 weeks. The information-only control will entail 1 online session (approx. 50 mins.) delivered via videoconference by a trained facilitator. Sleep data (collected via both actigraphy watches and patient self-report sleep diaries) and data on mood, grief, and sleep habits will be collected from participants at three timepoints (baseline, post-treatment, and then again at a 6-month follow-up).