Bacterial Infection Clinical Trial
Official title:
Bacterial Infections in People Who Inject Psychoactive Substances
Bacterial infections in people who inject psychoactive substances
In context of an increase of bacterial infections in people who inject psychoactive
substances (PS) all around the world and a lack of available scientific data, the
investigators decided to set up a descriptive study on bacterial infection types and
determinants in Injection Drug Users (IDUs).
Through a multidisciplinary approach between hospital departments (e.g. infectious diseases,
emergency and addictology), the local addiction management and liaison team (ELSA) and the
regional addictovigilance center, data were collected on appearance and course of bacterial
infections in IDUs hospitalized at Montpellier University Hospital, France.
This study aims to provide medical data in order to better understand those infections and
their determinants and provide information for potential future more specific observational
studies.
The regional addictovigilance center is a member of the French Addictovigilance Network,
which was established to monitor the potential for abuse and dependence of PS, and to provide
information on the risk of addiction and advice for public health decision making, under the
supervision of the French National Agency for Medicines and Health Products Safety. This
surveillance system is principally based on spontaneous reporting by healthcare professionals
and patients that is regulated by law. Collected data were extracted from those spontaneous
reports (composed by data from the medical file*, DxCare or notification by medical team).
First data were collected in 2012.
In addition, the investigators offered patients to fill in an anonymous questionnaire** on
hygiene habits which was not mandatory and had no influence on treatment, and was offered
during the ELSA team intervention (questions from the questionnaire are classical risk
reduction question on injection and hygiene practices).
Main results are the description of the infections and injection practices. There is no
control group per se as all included patients are IDUs and have a bacterial infection. But
the investigators infection (such as abscess or skin and soft tissue) and those with a
systemic infection. The two groups were established after the recruitment was completed. This
comparative analysis is only performed in order to better understand the development of
infections. Descriptive and comparative analyses was performed by the Department of Medical
Information.
*Data collected :
- Age
- Sex
- Past history of bacterial infection linked to injection of a psychoactive substance
- HIV and HCV status
- Injected psychoactive substance
- Injection practices (frequency, route, location)
- Diagnosis
- Bacterial analysis
- Treatments and course
- Hygiene questionnaire (attached file)
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02794831 -
Exposure to NSAIDs (Non Steroidal Anti-Inflammatory Drugs) and Severity of Community-acquired Bacterial Infections
|
||
Active, not recruiting |
NCT02533609 -
Elimination of Antibiotics During Citrate-anticoagulated Continuous-veno-venous-haemodialysis
|
||
Completed |
NCT01892358 -
Preventing Bacterial and Viral Infections Among Injection Drug Users
|
N/A | |
Completed |
NCT01371656 -
Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation
|
Phase 3 | |
Completed |
NCT01446289 -
Immune Response Induced by a Vaccine Against Group B Streptococcus and Safety in Pregnant Women and Their Offsprings
|
Phase 2 | |
Completed |
NCT01059890 -
Cerebral Antibiotics Distribution After Acute Brain Injury
|
Phase 1 | |
Completed |
NCT00389558 -
Antiseptic Use and Dressing Application
|
Phase 4 | |
Completed |
NCT00760279 -
An Open Label Evaluation of the Pharmacokinetics and Safety of Single Dose Intravenous Azithromycin in Preterm Neonates
|
Phase 1 | |
Completed |
NCT02311816 -
Increase in Procalcitonin Kinetics May be a Good Indicator of Starting Empirical Antibiotic Treatment in Critically Ill Patients
|
N/A | |
Completed |
NCT01225042 -
The Effect of Probiotics on E. Coli Gastroenteritis
|
N/A | |
Not yet recruiting |
NCT00765778 -
Mastering Hospital Antimicrobial Resistance and Its Spread Into the Community
|
N/A | |
Completed |
NCT00915213 -
Incidence of Antibiotic Resistant E.Coli in Patients Undergoing Repeat Prostate Biopsy
|
N/A | |
Completed |
NCT00800488 -
Procalcitonin for Predicting Serious Bacterial Infection in Infants Less Than 3 Months
|
N/A | |
Terminated |
NCT00307099 -
Comparative Antibiotic Therapy for Subjects With Pulmonary Infiltrates in the ICU
|
Phase 3 | |
Recruiting |
NCT04479657 -
Qingfei Granule for the Treatment of the Pediatric Acute Upper Respiratory Tract Infection With Bacterial Infection
|
Early Phase 1 | |
Completed |
NCT03299894 -
Impact of qSOFA Calculation on the Timing of Antimicrobial Therapy in the Emergency Department
|
N/A | |
Completed |
NCT01817075 -
Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant
|
Phase 3 | |
Completed |
NCT01244698 -
Postoperative Antibiotic Requirements Following Immediate Breast Reconstruction
|
Phase 4 | |
Completed |
NCT01250574 -
Neutrophil CD64 and Procalcitonin as Novel Biomarkers for Postoperative Infections
|
||
Completed |
NCT01012089 -
Study of the Pharmacokinetics of Daptomycin in Children With Renal Disease
|
N/A |