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Back Pain clinical trials

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NCT ID: NCT05614674 Not yet recruiting - Self Efficacy Clinical Trials

The Examination of Relationship Between Self-Efficacy in People With Chronic Low Back Pain

Start date: November 2022
Phase:
Study type: Observational [Patient Registry]

Self-efficacy is defined as a person's confidence or belief that one can achieve a certain behavioral or cognitive state. Self-efficacy is one of the most important assesment parameters in the self-management model. It is accepted that patients with chronic low back pain with high self-efficacy have a better prognosis than those with low self-efficacy. Due to the complex nature of pain; The relationship between psychological and physical parameters such as pain catastrophy, disability level, depression, physical performance, self-efficacy, pain intensity and fear avoidance arouses curiosity. The aim of this cross-sectional study is to examine the relationship between the level of self-efficacy and sensory, perceptual and motor skills in people with chronic low back pain.

NCT ID: NCT05614596 Recruiting - Low Back Pain Clinical Trials

Interventional Techniques for Managment of Chronic Low Back Pain

Start date: December 2022
Phase: N/A
Study type: Interventional

Identify the efficacy of difference procedures of imaging guidance for needles for interventional treatments of low back pain (LBP) associated with sciatica and to study results and satisfaction of the patients between different groups.

NCT ID: NCT05612308 Completed - Clinical trials for Non Specific Low Back Pain

Vertical Oscillatory Pressure and Sustained Natural Apophyseal Glides in ow Back Pain

VOP&SNAG
Start date: September 24, 2021
Phase: N/A
Study type: Interventional

Among different spinal manual therapies, which have been reported to be effective in the management of LBP are Sustained Natural Apophyseal Glide (SNAGS) and Vertical Oscillatory Pressure (VOP) . Vertical oscillatory pressure is a derivative of manipulative therapy whereby a gentle vertical manipulative oscillation is applied on spinal vertebrae and has been noted to be effective in management of low back pain . On the contrary, the SNAGS is a manipulative technique that is commonly used in the western countries and found to be effective in reducing pain and disability in the management of mechanical LBP . However, there are limited studies comparing the effects of SNAG and VOP on clinical and psychosocial variables in patients with mechanical LBP in Nigeria. Hence, this study aims at investigating the effects of Nwugarian VOP and SNAG techniques on selected clinical and psychosocial variables in patients with mechanical LBP.

NCT ID: NCT05611476 Completed - Chronic Pain Clinical Trials

Cognitive Muscular Therapy for Low Back Pain

CMT-LBP
Start date: December 8, 2022
Phase: N/A
Study type: Interventional

The primary aim of this study is to adapt Cognitive Muscular Therapy so that it can be used to manage chronic low back pain. A secondary aim is to understand the potential therapeutic benefit of this intervention.

NCT ID: NCT05610813 Active, not recruiting - Clinical trials for Chronic Non-specific Low Back Pain

Comparison of VER-01 to Opioids in Patients With Chronic Non-specific Low Back Pain

ELEVATE
Start date: June 8, 2023
Phase: Phase 3
Study type: Interventional

Randomized, open-label, parallel-group phase III trial to prove an additional benefit of the full-spectrum cannabis extract VER-01 over opioids in patients with chronic non-specific low back pain for whom drug treatment is indicated and previous optimized treatments with non-opioid analgesics have not led to sufficient pain relief or were unsuitable due to contraindications or intolerance.

NCT ID: NCT05607381 Recruiting - Low Back Pain Clinical Trials

Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain

Start date: November 30, 2022
Phase: N/A
Study type: Interventional

The purpose of this research study is to see how a mindfulness meditation-based intervention affects pain. Specifically, we are interested in understanding the pain-relieving brain mechanisms of mindfulness meditation-based therapy for patients with opioid-treated chronic low back pain.

NCT ID: NCT05606510 Recruiting - Back Pain Clinical Trials

The Effects of Mindful Exercise on Back Pain in Older Patients With Primary Osteoporosis

Start date: February 16, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized control trial is to determine the effects of a mindful exercise program on physical (back pain and balance) and psychological (mindfulness, kinesiophobia, anxiety and depression) consequences of primary osteoporosis in older patients. The main questions it aims to answer are: - What are the levels of pain, balance, mindfulness, kinesiophobia, anxiety and depression in older patients with primary osteoporosis? - Are there differences in pain, balance, mindfulness, kinesiophobia, anxiety and depression according to sociodemographic-clinical characteristics of the patients? - Are there differences in pain, balance, mindfulness, kinesiophobia, anxiety and depression between the intervention (mindful exercise) and control (usual care) groups of older patients with primary osteoporosis? 128 participants who meet the criteria will be recruited from the pain department of a Tertiary A level provincial Traditional Chinese Medicine hospital in Mainland China, and randomly assigned to the intervention group or control group. All patients in both groups will receive usual care, including routine medicine and nursing care. The study will last for 12 weeks (one-week training in hospital and 11-week on-line sessions at home) and 4-week follow up. Patients in the intervention group will receive a group-based mindful exercise which will be conducted 5 times per week, 30 minutes per session, and co-led by a mindfulness-trained main researcher and a professional exercise specialist for the first week (week 1) hospitalization. When they discharge, on-line sessions (week 2-12) will be conducted by the main researcher from Monday to Friday. Patients and primary caregivers will be taught how to use 'Tencent meet' software. Upon discharge, a WeChat group will be set up to notify the exercise time and send the links for the online sessions. Those in the control group will received routine medicine and nursing care as usual, and only be taught on the hospital-recommended movements (physical stretching) and encouraged to do it at home on their own. All the variables (pain, mindfulness, kinesiophobia, anxiety and depression) and the TUG test (balance) will be measured at the following time point: baseline (Time 1), week 4 (Time 2), week 8 (Time 3), week 12 (Time 4, immediately post-intervention) and week 16 (Time 5, 4 weeks after the intervention) for the two groups of patients. The study will obtain ethical clearance from the study setting, as well as written consent from the participants. Descriptive statistics will be computed for all variables. Normality and homogeneity of the variances will be tested using the Shapiro-Wilk and Levene tests, respectively. The data will be analyzed using mixed-model analysis of variance to test the main and interaction effects of group (independent factor) and time (repeated-measures factor) on the dependent variables. The findings of the study would certainly have implications for the treatment of older patients with primary osteoporosis, especially non-pharmacological treatment.

NCT ID: NCT05604027 Not yet recruiting - Clinical trials for Chronic Low-back Pain

Pain Types and Pain Severity in Chronic Low Back Pain

Start date: December 15, 2022
Phase:
Study type: Observational

The aim of this study is to characterize the distribution of pain phenotypes in people with chronic low back pain and to determine the effects of pain phenotypes on pain severity, functional status and quality of life. Participants will be examined to determine the type of pain and questions will be asked to identify the effects.

NCT ID: NCT05601843 Completed - Acute Pain Clinical Trials

Transcutaneous Electrical Nerve Stimulation for Back Pain in the Emergency Department (TENS-ED)

TENS-ED
Start date: May 8, 2023
Phase: N/A
Study type: Interventional

The effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) to reduce pain scores for patients with acute back pain in an ambulatory emergency department (ED) population will be examined in this dual-center, cluster randomized, controlled, open-label study.

NCT ID: NCT05601791 Recruiting - Low Back Pain Clinical Trials

Efficacy of PLDD Versus ESI in the Treatment of Lumbar Radicular Pain

Start date: November 30, 2021
Phase: N/A
Study type: Interventional

The most common cause of lumbar radicular pain is intervertebral disc herniation with or without pressure on the nerve root, which leads to inflammation and pain. Just as the mechanical component is important, so is the inflammatory component in the etiology of lumbar radicular pain. Numerous pro-inflammatory and anti-inflammatory proteins were found in serum, cerebrospinal fluid and disc biopsies from patients with lumbar radicular pain. Interleukin(IL)-1β, IL-6, IL-8, and tumor necrosis factor TNF-α are the most frequently investigated (8, 9). Elevated levels of IL-6 and TNF-α were found in patients with lumbar pain caused by intervertebral disc herniation. In order to avoid systemic and unwanted effects of analgesics, undergoing anesthesia and long-term and extensive operations, minimally invasive procedures are increasingly used in the treatment of lumbar radicular pain. Epidural administration of steroids and local anesthetic through a transforaminal approach (ESI TF) and percutaneous laser disc decompression (PLDD) are some of these methods. Lumbar radicular pain occurs due to inflammation and/or disc-radicular contact. Corticosteroids interrupt the inflammatory process, the transmission of pain signals via nociceptive C fibers and reduce capillary permeability. Along with the corticosteroid, a local anesthetic is also applied, which leads to immediate analgesia by blocking the conduction of painful impulses by blocking sodium channels. Percutaneous laser disc decompression (PLDD) is a minimally invasive method of treating lumbar radicular pain performed under local anesthesia under fluoroscopic control. The laser energy leads to the heating of the tissue of the nucleus pulposus, which leads to the evaporation of a small volume of water inside the disc. Viewing the disc as a closed hydraulic system, a small decrease in the water content within the disc leads to a disproportionate decrease in intradiscal pressure, which results in retraction of the herniated disc. Thermal energy leads to protein denaturation, which causes structural changes and thus prevents further retention of water in the disc, and a stable scar is created at the point of laser action. On the basis of current knowledge, an attempt is made to establish a link between inflammatory parameters as predictive and prognostic biomarkers in the treatment of patients with lumbar radicular pain caused by intervertebral disc herniation.