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NOX4 and Related Biomarkers in ADPKD

Autosomal Dominant Polycystic Kidney Disease Clinical Trial

Official title:
NOX4, Mitochondria and Related Biomarkers in Autosomal Dominant Polycystic Kidney Disease

Clinical Trial Summary

To determine the value of NOX4, markers of mitochondria injury and function, and oxidative stress as real-time biomarkers to assess disease severity in patients with early autosomal dominant polycystic kidney disease (ADPKD).

Clinical Trial Description

This will be a cross sectional study and will include male and female, young (15-40-years) well characterized patients with early (eGFR>70mL/min/1.73m2) ADPKD. Patients with different classes of disease severity will be selected using the ADPKD imaging classification. The study will include 60 class-1 (A-E) patients (N=12 per each sub-class). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04630613
Study type Observational [Patient Registry]
Source Mayo Clinic
Contact
Status Recruiting
Phase
Start date July 21, 2020
Completion date May 2024
View Details
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