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Autism Spectrum Disorder clinical trials

View clinical trials related to Autism Spectrum Disorder.

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NCT ID: NCT06431126 Active, not recruiting - Clinical trials for Autism Spectrum Disorder

Animal-assisted and Nature Based Activities

Start date: September 24, 2020
Phase: N/A
Study type: Interventional

Neuropsychiatric impairments in young adults are common and can involve social withdrawal, and difficulties in receiving support from healthcare and municipal social care services. Collaboration is needed, but knowledge gaps exist concerning effective interventions. Participation in meaningful activities, as a complement to other treatment strategies can be a step towards studies/work. The aim of the trial is to explore the feasibility of a structured nature and animal-based activity on a farm for young adults with neuropsychiatric impairments. The intervention involves participation in nature and animal-assisted group activities, twice a week for 12 weeks. Data consists of interviews with participants prior to and after the intervention, as well as one year later. The one-year follow-up focus is on life situation, changes in everyday life and experiences of the intervention. In addition, interview-based experiences of the ordinary staff and supervisors on the farm are included. Analysis will be carried out with qualitative content analysis, as well as health-economic calculations.

NCT ID: NCT06390683 Active, not recruiting - Clinical trials for Autism Spectrum Disorder

Biodiversity Interventions for Assisted Living Centers

BIWE
Start date: February 1, 2023
Phase: N/A
Study type: Interventional

Biodiversity is essential for nature and human well-being. Land use has reduced biodiversity in cities, which weakens the functionality of the urban ecosystems and the well-being of citizens. This may also increase the risk of immune-mediated disorders among urban dwellers. In Biodiversity interventions for assisted living centers (BIWE 2), microbial biodiversity interventions are performed to increase biodiversity in urban housing units for people with autism spectrum disorder, disabled people and elderly. Results from the intervention trials are combined with publicly available land cover and ecological data. These are analyzed from the viewpoint of shifts in ecosystems and human well-being and immune regulation, ecological quality, and urban planning. The investigators set up an intervention study in which yards of the housing units are rewilded with diverse vegetation and decaying deadwood and plant residuals. The investigators aim to evaluate the effect of rewilding, and yard management practices on commensal microbiome, cortisol levels and well-being and salivary cytokine levels, and gene pathways.

NCT ID: NCT06382909 Active, not recruiting - Clinical trials for Autism Spectrum Disorder

Effect of Probiotic Compound K11T e K11TMax in ASD

ASD
Start date: March 22, 2024
Phase: N/A
Study type: Interventional

The research is characterized as a randomized, double-blind clinical trial (phase III) in which administered the probiotic K11-T (with and without added amino acids, fatty acids and vitamins) to children between 3 and 11 years old with Autism Spectrum Disorder - ASD, being subsequently assessed outcomes related to inflammatory markers and neuropsychiatric and sociopedagogical criteria. To this end, the study will create three groups, one of which will be a control group, which will receive a placebo, the other will receive the probiotic without micronutrients and another will receive the probiotic with added nutrients.

NCT ID: NCT06373770 Active, not recruiting - Clinical trials for Autism Spectrum Disorder

Effects of Ayres Sensory Integration Therapy Versus Conservative Treatment in Autism Spectrum

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Effects of Ayres Sensory Integration Therapy Versus Conservative Treatment in Autism Spectrum

NCT ID: NCT06361147 Active, not recruiting - Clinical trials for Autism Spectrum Disorder

Psychoeducation of Adult Siblings of ASD People (Autism Spectrum Disorder).

Start date: March 28, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to apply a psychoeducational program in adult siblings of people with ASD as a means to provide knowledge related to the disorder and improving their quality of life. The psycho-educational program will be implemented in adult siblings of people with ASD and its effectiveness will be assessed. Participation in this program is expected to contribute in the improvement of the quality of life of the participants, their siblings with ASD and those related to them. No risk is identified.

NCT ID: NCT06348433 Active, not recruiting - Clinical trials for Autism Spectrum Disorder

Efficacy Evaluation and Mechanism Study of Ketogenic Diet on Autism Spectrum Disorder in Children

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder, which is characterized by social interaction and communication defects, rigid repetitive behaviors, and often accompanied by speech development retardation. According to the report released by the Morbidity and Mortality Weekly Report (MMWR) of the Centers for Disease Control and Prevention (CDC), according to the statistical data analysis in 2020, one out of every 36 8-year-old children (2.76%) was confirmed to have autism spectrum disorder (ASD). This ratio is higher than that published in December 2021, when the prevalence rate of 8-year-old children was 1/44 (2.3%) according to the statistics in 2018. Although ASD has a high incidence, there is still a lack of effective treatment measures for autism at present. Drug treatment can only partially alleviate some related symptoms, such as irritability and aggressiveness. Other interventions mainly focus on behavioral and educational interventions, which have limited help to patients. The high cost also leads to a huge burden on families and health care systems. Therefore, finding targeted treatment measures and treatment mechanisms for ASD as soon as possible has become an urgent problem for us to solve.Faced with limited treatment options, as many as a third of parents try various dietary pattern interventions to help their autistic children. In recent years, ketogenic diet, as a diet mode with extremely low carbohydrate, high fat, proper amount of protein and other nutrients, has attracted wide attention. In this mode, increased lipolysis puts the body in a ketosis state, thus ensuring energy supply.Although ketogenic diet (KD) has been proved to be effective in reducing the core symptoms in autistic patients and mouse models, the specific mechanism of KD in autism spectrum disorder (ASD) is still not completely clear.This study aims to evaluate the efficacy of ketogenic diet in improving core symptoms, sleep disorders and gastrointestinal symptoms of ASD children, explore the changes of excitation/inhibition (dorsolateral prefrontal cortex) in prefrontal cortex of ASD children before and after ketogenic diet intervention, and try to reveal the mechanism of ketogenic diet in treating ASD.

NCT ID: NCT06303791 Active, not recruiting - Clinical trials for Autism Spectrum Disorder

Digital-based Psychosocial Intervention for Parents of Children With Neurodevelopmental Disorders

INPSYD
Start date: September 7, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to implement a structured psychosocial intervention program with digital support (randomized and with a control group) that will be conducted virtually and synchronously to families of children with autism spectrum disorder (ASD) and families of children with Attention Deficit with hyperactivity Disorder (ADHD). The main questions it aims to answer are: 1. Will the program impact on different variables in the parents' domain (parental stress variables, quality of life/social support and coping skills), 2. Will the program impact on different variables in the children's domain (daily life functioning, social behavioral variables, and executive functioning). 3. Treatment outcomes will be assessed at pre-test, post-test, and 6-month follow-up assessment across intervention and control groups using a battery of measures of parenting stress, coping skills, social support, and children's dysfunctional outcomes Parents and teachers will complete different questionnaires to see if there are improvements on parent's and children outcomes. Researchers will compare intervention group and control group to see if there are improvements on parent's domains (parenting stress, coping skills, social support) and children's dysfunctional outcomes (daily life functioning, social behavioral variables, and executive functioning).

NCT ID: NCT06281171 Active, not recruiting - Clinical trials for Autism Spectrum Disorder

Evaluation of SkillTalk for Autistic Young Adults

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the effectiveness of using a Microskills video training library for young adults, aged 18-28, with autism spectrum disorder (ASD) to enhance their skills in developing and maintaining healthy relationships. The main questions it aims to answer are: - Does using SkillTalk increase autistic young adults skills in the communications skills that are demonstrated in the video curriculum (skills: resolve conflict, compromise, give feedback)? - Does using SkillTalk increase reported confidence and satisfaction in communication and relationship skills? - Does using SkillTalk increase interpersonal competence? - Does using SkillTalk increase ability to cope with rejection? - Does using SkillTalk improve mental health and wellbeing? Participants will be asked to: - Take a survey at the beginning of the study, after one month the end of the study, and at 3-month follow up - Participate in recorded video calls with projects staff, comprised of 2-3 brief roleplay scenarios of relationship skills at the beginning of the study, after one month the end of the study, and at 3-month follow up - Watch a minimum of 85% of the 60 minutes of video assigned

NCT ID: NCT06259539 Active, not recruiting - Clinical trials for Autism Spectrum Disorder

A YouTube Curriculum for Children With Autism and Obesity

Start date: September 7, 2023
Phase: N/A
Study type: Interventional

Parents as primary caregivers play an important role in shaping children's mealtime and eating behaviors; and in preventing weight gain. Conventionally, in-person, parent-implemented treatments have worked well for children with autism, however, post-COVID-19 pandemic there is a need for virtual, evidence-based training for parents to improve nutrition in children with autism and weight issues. This study aims to: a) increase self-efficacy among parents of children with autism and overweight or obesity to feed their children a healthy diet, b) improve parental nutrition knowledge and skills on how to feed their child with autism and overweight or obesity a healthier diet, c) improve their child's mealtime behaviors, and d) increase the child's dietary variety.

NCT ID: NCT06246890 Active, not recruiting - Clinical trials for Autism Spectrum Disorder

Autism ALERT Expansion

Start date: January 30, 2024
Phase:
Study type: Observational [Patient Registry]

Autism Access Link for Early Referral and Treatment [ALERT], the intervention proposed in this application, is a novel state-wide referral and case management platform that PCPs can activate to ensure that a child with suspected ASD receives all necessary ASD diagnosis and treatment resources in a single referral, radically simplifying a complex diagnostic and treatment process. We hypothesize that Autism ALERT will have strong acceptability and high rates of use among primary care providers as well as among diverse low-income parents of children at risk for ASD, and that we will see increased rate of child ASD educational evaluations within six months, and shortened time between referral and ASD treatment.